Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request

Ultrasound-guided parasternal intercostal nerve block for postoperative analgesia in mediastinal mass resection by median sternotomy: a randomized, double-blind, placebo-controlled trial.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي
  • معلومة اضافية
    • المصدر:
      Publisher: BioMed Central Country of Publication: England NLM ID: 100968535 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2253 (Electronic) Linking ISSN: 14712253 NLM ISO Abbreviation: BMC Anesthesiol Subsets: MEDLINE
    • بيانات النشر:
      Original Publication: [London] : BioMed Central, 2001-
    • الموضوع:
      Sternotomy* ; Ultrasonography, Interventional*; Intercostal Muscles/*diagnostic imaging ; Mediastinal Neoplasms/*surgery ; Nerve Block/*methods; Adult ; Analgesia, Patient-Controlled ; Analgesics, Opioid/administration & dosage ; Double-Blind Method ; Drug Utilization/statistics & numerical data ; Female ; Humans ; Male ; Middle Aged ; Pectoralis Muscles/diagnostic imaging ; Prospective Studies ; Sufentanil/administration & dosage
    • نبذة مختصرة :
      Background: Ultrasound-guided parasternal intercostal nerve block is rarely used for postoperative analgesia, and its value remains unclear. This study aimed to evaluate the effectiveness of ultrasound-guided parasternal intercostal nerve block for postoperative analgesia in patients undergoing median sternotomy for mediastinal mass resection.
      Methods: This randomized, double-blind, placebo-controlled trial performed in Renmin Hospital, Wuhan University, enrolled 41 participants aged 18-65 years. The patients scheduled for mediastinal mass resection by median sternotomy were randomly assigned were randomized into 2 groups, and preoperatively administered 2 injections of ropivacaine (PSI) and saline (control) groups, respectively, in the 3rd and 5th parasternal intercostal spaces with ultrasound-guided (USG) bilateral parasternal intercostal nerve block. Sufentanil via patient-controlled intravenous analgesia (PCIA) was administered to all participants postoperatively. Pain score, total sufentanil consumption, and postoperative adverse events were recorded within the first 24 h.
      Results: There were 20 and 21 patients in the PSI and control group, respectively. The PSI group required 20% less PCIA-sufentanil compared with the control group (54.05 ± 11.14 μg vs. 67.67 ± 8.92 μg, P < 0.001). In addition, pain numerical rating scale (NRS) scores were significantly lower in the PSI group compared with control patients, both at rest and upon coughing within 24 postoperative hours. Postoperative adverse events were generally reduced in the PSI group compared with controls.
      Conclusions: USG bilateral parasternal intercostal nerve block effectively reduces postoperative pain and adjuvant analgesic requirement, with good patient satisfaction, therefore constituting a good option for mediastinal mass resection by median sternotomy.
    • References:
      Arch Iran Med. 2016 Dec;19(12):870-876. (PMID: 27998163)
      J Orthop Surg Res. 2020 May 26;15(1):191. (PMID: 32456647)
      BMJ. 2010 Mar 23;340:c332. (PMID: 20332509)
      Reg Anesth Pain Med. 2015 Jul-Aug;40(4):388. (PMID: 26079353)
      Anesthesiology. 2003 Oct;99(4):918-23. (PMID: 14508326)
      Paediatr Anaesth. 2019 May;29(5):519-529. (PMID: 30861264)
      Eur J Cardiothorac Surg. 2014 Mar;45(3):e68-73; discussion e73. (PMID: 24321994)
      J Anesth. 2016 Oct;30(5):916. (PMID: 27325411)
      J Clin Diagn Res. 2014 Feb;8(2):77-80. (PMID: 24701488)
      Reg Anesth Pain Med. 2017 Nov/Dec;42(6):698-708. (PMID: 28937533)
      Reg Anesth Pain Med. 2016 May-Jun;41(3):411-2. (PMID: 27093277)
      Anaesthesist. 2019 Dec;68(12):848-851. (PMID: 31768562)
      J Pain Res. 2020 Apr 30;13:865-871. (PMID: 32431534)
      Anesthesiology. 2006 May;104(5):1047-53. (PMID: 16645458)
      Anesth Analg. 2005 Jan;100(1):25-32. (PMID: 15616047)
      BMC Anesthesiol. 2020 May 23;20(1):123. (PMID: 32446304)
      Medicine (Baltimore). 2019 Aug;98(32):e16732. (PMID: 31393382)
      Thorac Cardiovasc Surg. 2020 Aug;68(5):410-416. (PMID: 30114712)
      Semin Cardiothorac Vasc Anesth. 2016 Sep;20(3):205-12. (PMID: 25900900)
      Eur J Pain. 2018 Oct;22(9):1673-1677. (PMID: 29770535)
      JAMA Surg. 2017 Jul 1;152(7):691-697. (PMID: 28564673)
      Best Pract Res Clin Anaesthesiol. 2019 Mar;33(1):67-77. (PMID: 31272655)
      Br J Hosp Med (Lond). 2015 Oct;76(10):570-5. (PMID: 26457937)
      J Cardiothorac Vasc Anesth. 2018 Apr;32(2):915-927. (PMID: 29169795)
      Pain Physician. 2019 Jul;22(4):E315-E323. (PMID: 31337173)
      Anaesthesia. 1996 Sep;51(9):805-7. (PMID: 8882237)
      Biomed Res Int. 2018 Jan 21;2018:9404508. (PMID: 29581990)
      J Cardiothorac Vasc Anesth. 2012 Jun;26(3):439-42. (PMID: 22176767)
      J Cardiothorac Vasc Anesth. 2007 Aug;21(4):547-53. (PMID: 17678782)
      Curr Med Res Opin. 2011 Feb;27(2):439-48. (PMID: 21194392)
      Acta Anaesthesiol Scand. 2001 Sep;45(8):935-9. (PMID: 11576042)
      J Clin Anesth. 2015 Dec;27(8):696. (PMID: 26144912)
    • Contributed Indexing:
      Keywords: Median sternotomy; Mediastinal mass; Postoperative analgesia; Resection; Ultrasound-guided parasternal intercostal nerve block
    • الرقم المعرف:
      0 (Analgesics, Opioid)
      AFE2YW0IIZ (Sufentanil)
    • الموضوع:
      Date Created: 20210331 Date Completed: 20211228 Latest Revision: 20240331
    • الموضوع:
      20240331
    • الرقم المعرف:
      PMC8011112
    • الرقم المعرف:
      10.1186/s12871-021-01291-z
    • الرقم المعرف:
      33784983