Pilot study of tolerability and safety of opioid receptor antagonists as novel therapies for chronic pain among persons living with HIV with past year heavy drinking: a randomized controlled trial.

Publisher: Informa Healthcare Country of Publication: England NLM ID: 8915313 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1360-0451 (Electronic) Linking ISSN: 09540121 NLM ISO Abbreviation: AIDS Care Subsets: MEDLINE

Publication: London : Informa Healthcare
Original Publication: Abingdon, Oxfordshire, U.K. : Carfax Pub. Co., c1989-

Alcoholism* ; Chronic Pain*/drug therapy ; HIV Infections*/complications ; HIV Infections*/drug therapy; Humans ; Narcotic Antagonists/therapeutic use ; Naltrexone/therapeutic use ; Pilot Projects ; Treatment Outcome

Clinical Trial Registration: ClinicalTrials.gov identifier: NCT03278886.

Arch Intern Med. 2006 May 22;166(10):1092-7. (PMID: 16717171)
PLoS One. 2017 Aug 29;12(8):e0183821. (PMID: 28850596)
Ann Rheum Dis. 2014 Jun;73(6):968-74. (PMID: 24665116)
J Am Coll Cardiol. 2006 Nov 7;48(9):1871-9. (PMID: 17084265)
AIDS Care. 2000 Jun;12(3):255-66. (PMID: 10928201)
Health Qual Life Outcomes. 2004 Feb 26;2:12. (PMID: 14987333)
Brain Res. 2000 Jan 31;854(1-2):224-9. (PMID: 10784126)
J Pain Symptom Manage. 2011 Dec;42(6):893-902. (PMID: 21802896)
BMC Public Health. 2011 Oct 06;11:770. (PMID: 21978149)
HIV Clin Trials. 2011 May-Jun;12(3):161-70. (PMID: 21684856)
Eur J Neurosci. 2008 Jul;28(1):20-9. (PMID: 18662331)
J Leukoc Biol. 2006 Jun;79(6):1166-72. (PMID: 16574767)
J Pain. 2012 Jul;13(7):704-13. (PMID: 22748803)
Lancet. 2019 Oct 26;394(10208):1560-1579. (PMID: 31657732)
Addiction. 2007 May;102(5):752-60. (PMID: 17506152)
J Pain Symptom Manage. 2008 Jan;35(1):95-102. (PMID: 17980999)
Clin Infect Dis. 2017 Oct 30;65(10):e1-e37. (PMID: 29020263)
Clin Rheumatol. 2014 Apr;33(4):451-9. (PMID: 24526250)
J Int AIDS Soc. 2014 Feb 18;17:18719. (PMID: 24560338)
Pain. 2011 Dec;152(12):2757-2764. (PMID: 21962911)
Addiction. 2013 Oct;108(10):1779-87. (PMID: 23773361)
J Acquir Immune Defic Syndr. 2012 Oct 1;61(2):164-70. (PMID: 22766967)
J Pharmacol Exp Ther. 2000 May;293(2):607-17. (PMID: 10773035)
Addiction. 2008 Dec;103(12):1996-2005. (PMID: 18855809)
AIDS Behav. 2016 Mar;20(3):583-9. (PMID: 26438486)
Qual Life Res. 1997 Aug;6(6):481-93. (PMID: 9330549)
Pain Pract. 2014 Mar;14(3):207-16. (PMID: 23551857)
AIDS Patient Care STDS. 2015 Apr;29(4):186-92. (PMID: 24984142)
Arch Intern Med. 1998 Mar 23;158(6):626-32. (PMID: 9521227)
Ann Rheum Dis. 2015 Jan;74(1):4-7. (PMID: 24914071)
Pain. 2016 Apr;157(4):931-937. (PMID: 26683238)
Drug Alcohol Depend. 2001 Nov 1;64(3):257-63. (PMID: 11672940)
Med Care. 2004 Feb;42(2):129-38. (PMID: 14734950)
Med Hypotheses. 2009 Mar;72(3):333-7. (PMID: 19041189)
Pain. 2005 Dec 15;119(1-3):124-132. (PMID: 16297562)
MMWR Recomm Rep. 2016 Mar 18;65(1):1-49. (PMID: 26987082)
Drug Alcohol Depend. 2014 Nov 1;144:87-92. (PMID: 25220898)
BMC Psychiatry. 2011 May 04;11:75. (PMID: 21542929)
J Ambul Care Manage. 2004 Jul-Sep;27(3):263-80. (PMID: 15287216)
Arthritis Rheum. 2013 Feb;65(2):529-38. (PMID: 23359310)

U24 AA020779 United States AA NIAAA NIH HHS; UH2 AA026193 United States AA NIAAA NIH HHS; U24 AA020778 United States AA NIAAA NIH HHS; P30 AI027757 United States AI NIAID NIH HHS; P30 AI042853 United States AI NIAID NIH HHS; UH3 AA026193 United States AA NIAAA NIH HHS

Keywords: HIV; Pain; alcohol; nalmefene; naltrexone

ClinicalTrials.gov NCT03278886

0 (Narcotic Antagonists)
5S6W795CQM (Naltrexone)

Date Created: 20210308 Date Completed: 20230707 Latest Revision: 20240802

20240802

PMC8421451

10.1080/09540121.2021.1896663

33682527