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Using Laser-Doppler Flowmetry to Evaluate the Therapeutic Response in Dentin Hypersensitivity.
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- معلومة اضافية
- المصدر:
Publisher: MDPI Country of Publication: Switzerland NLM ID: 101238455 Publication Model: Electronic Cited Medium: Internet ISSN: 1660-4601 (Electronic) Linking ISSN: 16604601 NLM ISO Abbreviation: Int J Environ Res Public Health Subsets: MEDLINE
- بيانات النشر:
Original Publication: Basel : MDPI, c2004-
- الموضوع:
- نبذة مختصرة :
Dentin hypersensitivity (DH) is a common medical condition with underreported prevalence and it is difficult to quantify. This study aimed to investigate whether assessing dental pulp vascular micro-dynamics by laser-Doppler flowmetry (LDF) would be functional for therapeutic evaluation, in contrast to a verbal rating scale (VRS). A split-mouth single-blind randomized study was conducted on seven patients and a total of 36 teeth. Two DH therapeutic methods were employed: (i) fluoride gel; (ii) Nd:YAG radiation combined with fluoride gel. For each tooth, five consecutive LDF determinations of pulp blood flow were made (before and immediately after desensitizing treatment, then after 24 h, 7 days, and 1 month), and the VRS was applied each time. Spearman's correlation was applied for concurrent validation. Two-way (treatment and patient) repeated measures ANOVA full factorial was applied, followed by Tukey's post-hoc comparisons and Pillai's trace multivariate statistic. While VRS scores had moderate reliability, LDF could objectively estimate treatment effects. Based on partial eta-squared values, treatment and patient characteristics were estimated to explain about 84% and 50% of the variability, respectively. In conclusion, LDF is an objective technique that can quantitatively assess DH evolution, and it is effective in reliably monitoring oral health therapeutic interventions.
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- Contributed Indexing:
Keywords: dentin hypersensitivity; laser Doppler flowmetry; microcirculation; outcome assessment; therapeutic research
- الرقم المعرف:
0 (Dentin Desensitizing Agents)
- الموضوع:
Date Created: 20201201 Date Completed: 20210211 Latest Revision: 20210211
- الموضوع:
20221213
- الرقم المعرف:
PMC7731012
- الرقم المعرف:
10.3390/ijerph17238787
- الرقم المعرف:
33256192
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