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[Gayet-Wernicke encephalopathy: clinical features and radiological anomalies].

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  • معلومة اضافية
    • Transliterated Title:
      L’encéphalopathie de Gayet Wernicke: aspects cliniques et anomalies radiologiques.
    • المصدر:
      Publisher: African Field Epidemiology Network Country of Publication: Uganda NLM ID: 101517926 Publication Model: eCollection Cited Medium: Internet ISSN: 1937-8688 (Electronic) NLM ISO Abbreviation: Pan Afr Med J Subsets: MEDLINE
    • بيانات النشر:
      Original Publication: Kampala, Uganda : African Field Epidemiology Network
    • الموضوع:
      Brain/*diagnostic imaging ; Thiamine Deficiency/*complications ; Wernicke Encephalopathy/*diagnostic imaging; Adult ; Alcoholism/complications ; Female ; Humans ; Magnetic Resonance Imaging ; Male ; Malnutrition/complications ; Middle Aged ; Vomiting/complications ; Wernicke Encephalopathy/physiopathology ; Young Adult
    • نبذة مختصرة :
      Gayet Wernicke encephalopathy (EGW) is a neurological emergency secondary to thiamine deficiency (vitamin B1). This is more often secondary to chronic alcoholism. The purpose of this study is to remind clinicians of some clinical signs different from ethylism, suggesting EGW as well as to report four cases characterized by different types of anomalies shown by MRI. The average age of patients was 40 years (2 females 2 males). The neurological picture was characterized by disorders of vigilance in all patients, oculomotor disorders in 2 cases, and cerebellar ataxia in one patient. Chronic vomiting was reported in two cases, prolonged fasting in the first case and alcoholism in the second case. MRI of the brain showed anomalies suggesting EGW in all patients with contrast enhancement in one case. Thiamin deficiency was confirmed in two patients. In our context EGW seems to be more frequent in pathological circumstances other than chronic alcoholism (chronic vomiting, severe malnutrition, severe starvation, and chemotherapy...). The clinical signs can suggest other pathologies such as cerebral venous thrombosis, stroke, or other metabolic disorders but MRI excluded them and allowed the diagnosis of EGW. MRI of the brain has an essential role in the diagnosis of EGW. Absence or delay in treatment may influence the prognosis.
      Competing Interests: Les auteurs ne déclarent aucun conflit d´intérêts.
      (Copyright: Siham Bouchal et al.)
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    • Contributed Indexing:
      Keywords: Gayet Wernicke encephalopathy; MRI anomalies; clinical; context
    • الموضوع:
      Date Created: 20201005 Date Completed: 20210106 Latest Revision: 20210106
    • الموضوع:
      20231215
    • الرقم المعرف:
      PMC7519788
    • الرقم المعرف:
      10.11604/pamj.2020.36.259.14410
    • الرقم المعرف:
      33014255