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Image smoothing using regularized entropy minimization and self-similarity for the quantitative analysis of drug diffusion.

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  • معلومة اضافية
    • المصدر:
      Publisher: Medknow Publications Country of Publication: India NLM ID: 101249598 Publication Model: Print Cited Medium: Internet ISSN: 1998-4138 (Electronic) Linking ISSN: 19984138 NLM ISO Abbreviation: J Cancer Res Ther Subsets: MEDLINE
    • بيانات النشر:
      Original Publication: Mumbai, India : Medknow Publications
    • الموضوع:
      Algorithms*; Antineoplastic Agents/*metabolism ; Delayed-Action Preparations/*metabolism ; Drug Delivery Systems/*methods ; Image Processing, Computer-Assisted/*methods ; Liver Neoplasms/*metabolism ; Magnetic Resonance Imaging/*methods; Diffusion ; Entropy ; Humans ; Liver Neoplasms/pathology
    • نبذة مختصرة :
      Background: Targetable drug delivery is an important method for the treatment of liver tumors. For the quantitative analysis of drug diffusion, the establishment of a method for information collection and characterization of extracellular space is developed by imaging analysis of magnetic resonance imaging (MRI) sequences. In this paper, we smoothed out interferential part in scanned digital MRI images.
      Materials and Methods: Making full use of priors of low rank, nonlocal self-similarity, and regularized sparsity-promoting entropy, a block-matching regularized entropy minimization algorithm is proposed. Sparsity-promoting entropy function produces much sparser representation of grouped nonlocal similar blocks of image by solving a nonconvex minimization problem. Moreover, an alternating direction method of multipliers algorithm is proposed to iteratively solve the problem above.
      Results and Conclusions: Experiments on simulated and real images reveal that the proposed method obtains better image restorations compared with some state-of-the-art methods, where most information is recovered and few artifacts are produced.
      Competing Interests: None
    • Contributed Indexing:
      Keywords: Entropy; extracellular space; image smoothing; low rank; nonconvex minimization; nonlocal self-similarity; targetable drug delivery
    • الرقم المعرف:
      0 (Antineoplastic Agents)
      0 (Delayed-Action Preparations)
    • الموضوع:
      Date Created: 20201002 Date Completed: 20201204 Latest Revision: 20220417
    • الموضوع:
      20221213
    • الرقم المعرف:
      10.4103/jcrt.JCRT_656_20
    • الرقم المعرف:
      33004766