A brief questionnaire measure of multidimensional schizotypy predicts interview-rated symptoms and impairment.

Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Original Publication: San Francisco, CA : Public Library of Science

Schizophrenic Psychology* ; Severity of Illness Index*; Schizotypal Personality Disorder/*diagnosis ; Surveys and Questionnaires/*standards; Adolescent ; Adult ; Female ; Humans ; Male ; Psychometrics ; Reproducibility of Results ; Schizotypal Personality Disorder/psychology ; Young Adult

Competing Interests: The authors have declared that no competing interests exist.
The present study employed structured diagnostic interviews to assess the construct validity of the brief version of the Multidimensional Schizotypy Scale (MSS-B), which was developed to assess positive, negative, and disorganized dimensions of schizotypy. It was hypothesized that the MSS-B subscales would be associated with differential patterns of symptoms and impairment, comparable to findings for the full-length MSS. A total of 177 young adults completed structured diagnostic interviews assessing symptoms and impairment. As hypothesized, MSS-B positive schizotypy was significantly associated with interview ratings of positive (psychotic-like) symptoms, as well as schizotypal and paranoid personality disorder traits. MSS-B negative schizotypy was associated with interview ratings of negative symptoms, as well as schizoid, paranoid, and schizotypal traits. Furthermore, negative schizotypy predicted Cluster A personality disorder diagnoses. MSS-B disorganized schizotypy was associated with interview ratings of disorganized symptoms. All three schizotypy dimensions were associated with impaired functioning. This was the first study to evaluate the validity of the MSS-B using interview measures, and the pattern of findings for each MSS-B subscale was closely comparable to the findings for the full-length MSS. Contrary to our hypothesis, cannabis use was largely unassociated with psychotic-like symptoms and did not moderate the expression of the schizotypy dimensions. The MSS-B has good psychometric properties, high concordance with the full-length MSS, and good construct validity. Thus, it appears to be a promising brief alternative to traditional schizotypy measures.

J Abnorm Psychol. 2005 Feb;114(1):170-5. (PMID: 15709824)
J Abnorm Psychol. 2020 Jul;129(5):492-504. (PMID: 32250141)
J Abnorm Psychol. 1978 Aug;87(4):399-407. (PMID: 681612)
Schizophr Res. 2013 Apr;145(1-3):50-5. (PMID: 23402694)
Schizophr Res. 2018 Mar;193:209-217. (PMID: 28735642)
Schizophr Res. 2011 Mar;126(1-3):1-10. (PMID: 21123033)
J Abnorm Psychol. 1996 Feb;105(1):114-23. (PMID: 8666700)
Schizophr Bull. 2008 May;34(3):444-57. (PMID: 17768308)
Personal Disord. 2020 Jul;11(4):260-269. (PMID: 31886688)
Schizophr Bull. 1995;21(1):19-31. (PMID: 7770738)
Biol Psychiatry. 2016 Apr 1;79(7):549-56. (PMID: 26386480)
Psychiatry Res. 2018 Dec;270:1143-1149. (PMID: 30366639)
Assessment. 2020 Jan 19;:1073191119900008. (PMID: 31955588)
Psychiatry Res. 2018 Mar;261:7-13. (PMID: 29272752)
J Abnorm Psychol. 1998 Nov;107(4):558-65. (PMID: 9830243)
Psychiatry Res. 2017 Jun;252:289-295. (PMID: 28288440)
Schizophr Res. 2009 May;110(1-3):1-23. (PMID: 19328655)
Schizophr Bull. 2015 Mar;41 Suppl 2:S366-73. (PMID: 25548387)
JAMA Psychiatry. 2013 Jan;70(1):107-20. (PMID: 23165428)
Schizophr Bull. 1991;17(4):555-64. (PMID: 1805349)
Psychol Assess. 2000 Mar;12(1):102-11. (PMID: 10752369)
J Pers Assess. 2020 Jul-Aug;102(4):508-515. (PMID: 31012748)
Schizophr Res. 2005 Oct 15;78(2-3):293-6. (PMID: 16054803)
Schizophr Res. 2019 Sep;211:36-43. (PMID: 31383512)
Psychol Med. 2008 Sep;38(9):1267-76. (PMID: 18205966)
J Abnorm Psychol. 1994 May;103(2):171-83. (PMID: 8040487)
Schizophr Bull. 2015 Mar;41 Suppl 2:S374-85. (PMID: 25810054)
Psychol Bull. 1992 Jul;112(1):155-9. (PMID: 19565683)
J Abnorm Psychol. 2013 Aug;122(3):807-15. (PMID: 24016018)

Date Created: 20200811 Date Completed: 20201008 Latest Revision: 20201008

20250114

PMC7416934

10.1371/journal.pone.0237614

32776979