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Combination Bacillus Calmette-Guérin and indoleamine 2,3-dioxygenase 1 inhibitor therapy of murine orthotopic bladder cancer.

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اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي
  • معلومة اضافية
    • المصدر:
      Publisher: Blackwell Science Country of Publication: England NLM ID: 100886721 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-410X (Electronic) Linking ISSN: 14644096 NLM ISO Abbreviation: BJU Int Subsets: MEDLINE
    • بيانات النشر:
      Original Publication: Oxford, UK : Blackwell Science, c1999-
    • الموضوع:
      Acetamides*/pharmacology ; Acetamides*/therapeutic use ; Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/therapeutic use ; BCG Vaccine*/pharmacology ; BCG Vaccine*/therapeutic use ; Quinolines*/pharmacology ; Quinolines*/therapeutic use ; Urinary Bladder Neoplasms*/chemistry ; Urinary Bladder Neoplasms*/drug therapy; Indoleamine-Pyrrole 2,3,-Dioxygenase/*antagonists & inhibitors; Animals ; Kynurenine/blood ; Mice ; Neoplasms, Experimental/chemistry ; Neoplasms, Experimental/drug therapy ; Urinary Bladder/chemistry ; Urinary Bladder/drug effects
    • References:
      Witjes JA. Management of BCG failures in superficial bladder cancer: a review. Eur Urol 2006; 49: 790-7.
      Luo Y, Chen X, O’Donnell MA. Role of Th1 and Th2 cytokines in BCG-induced IFN-γ production: cytokine promotion and simulation of BCG effect. Cytokine 2003; 21: 17-26.
      Cheong JE, Sun L. Targeting the IDO1/TDO2-KYN-AhR pathway for cancer immunotherapy - challenges and opportunities. Trends Pharmacol Sci 2018; 39: 307-25.
      Tham SM, Esuvaranathan K, Mahendran R. A murine orthotopic bladder tumor model and tumor detection system. J Vis Exp 2017; 119: e55078. https://doi.org/10.3791/55078.
      Von Rundstedt FC, Lerner SP Bacille-Calmette-Guerin non-responders: how to manage. Transl Androl Urol. 2015; 4: 244-53.
      Liu YR, Yin PN, Silvers CR, Lee Y-F. Enhanced metastatic potential in the MB49 urothelial carcinoma model. Sci Rep 2019; 9: 7425. https://doi.org/10.1038/s41598-019-43641-5.
      Hahn NM, Chang SS, Meng M et al. A phase II, randomized study of nivolumab (nivo) or nivo plus BMS-986205 with or without intravesical Bacillus Calmette-Guerin (BCG) in BCG-unresponsive, high-risk, non-muscle invasive bladder cancer (NMIBC): CheckMate 9UT. J Clin Oncol 2019; 37(Suppl): TPS493. https://doi.org/10.1200/JCO.2019.37.7_suppl.TPS493.
    • Grant Information:
      NUHSRO/2018/041/Innov/03 International National University Health System (NUHS) Innovation Grant
    • الرقم المعرف:
      0 (Acetamides)
      0 (Antineoplastic Agents)
      0 (BCG Vaccine)
      0 (Indoleamine-Pyrrole 2,3,-Dioxygenase)
      0 (Quinolines)
      0A7729F42K (linrodostat)
      343-65-7 (Kynurenine)
    • الموضوع:
      Date Created: 20200810 Date Completed: 20210205 Latest Revision: 20210205
    • الموضوع:
      20250114
    • الرقم المعرف:
      10.1111/bju.15201
    • الرقم المعرف:
      32770708