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Before Watson and Crick in 1953 Came Friedrich Miescher in 1869.

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اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي
  • المؤلفون: Lamm E;Lamm E; Harman O; Harman O; Veigl SJ; Veigl SJ
  • المصدر:
    Genetics [Genetics] 2020 Jun; Vol. 215 (2), pp. 291-296.
  • نوع النشر :
    Biography; Historical Article; Journal Article; Research Support, Non-U.S. Gov't
  • اللغة:
    English
  • معلومة اضافية
    • المصدر:
      Publisher: Oxford University Press Country of Publication: United States NLM ID: 0374636 Publication Model: Print Cited Medium: Internet ISSN: 1943-2631 (Electronic) Linking ISSN: 00166731 NLM ISO Abbreviation: Genetics Subsets: MEDLINE
    • بيانات النشر:
      Publication: 2021- : [Oxford] : Oxford University Press
      Original Publication: Austin, Tex. [etc.]
    • الموضوع:
      Genetic Code*; DNA/*genetics ; DNA/*history ; Genetics/*history; History, 19th Century ; History, 20th Century ; Humans
    • الموضوع:
      Miescher F
    • نبذة مختصرة :
      In 1869, the young Swiss biochemist Friedrich Miescher discovered the molecule we now refer to as DNA, developing techniques for its extraction. In this paper we explain why his name is all but forgotten, and his role in the history of genetics is mostly overlooked. We focus on the role of national rivalries and disciplinary turf wars in shaping historical memory, and on how the story we tell shapes our understanding of the science. We highlight that Miescher could just as correctly be portrayed as the person who understood the chemical nature of chromatin (before the term existed), and the first to suggest how stereochemistry might serve as the basis for the transmission of hereditary variation.
      (Copyright © 2020 by the Genetics Society of America.)
    • References:
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      Stud Hist Philos Biol Biomed Sci. 2015 Oct;53:40-52. (PMID: 26209888)
      Med Hist. 1969 Oct;13(4):377-82. (PMID: 4899817)
      J Hist Biol. 2020 Sep;53(3):451-484. (PMID: 32524311)
      Philos Rev. 1984;93:335-73. (PMID: 11617920)
      Hum Genet. 2008 Jan;122(6):565-81. (PMID: 17901982)
      Sci Context. 1995 Winter;8(4):609-34. (PMID: 11613275)
      Dev Biol. 2005 Feb 15;278(2):274-88. (PMID: 15680349)
      Sci Am. 1968 Jun;218(6):78-88. (PMID: 5648255)
    • الرقم المعرف:
      9007-49-2 (DNA)
    • الموضوع:
      Date Created: 20200604 Date Completed: 20210706 Latest Revision: 20240729
    • الموضوع:
      20240729
    • الرقم المعرف:
      PMC7268995
    • الرقم المعرف:
      10.1534/genetics.120.303195
    • الرقم المعرف:
      32487691