Cellular immune response to acute exercise: Comparison of endurance and resistance exercise.

Publisher: Blackwell Country of Publication: England NLM ID: 8703985 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0609 (Electronic) Linking ISSN: 09024441 NLM ISO Abbreviation: Eur J Haematol Subsets: MEDLINE

Publication: <2005->: Oxford : Blackwell
Original Publication: Copenhagen : Munksgaard, c1987-

Immunity, Cellular*; Exercise/*physiology; Chemotaxis, Leukocyte/immunology ; Humans ; Leukocyte Count ; Leukocytes/immunology ; Leukocytes/metabolism ; Lymphocyte Count ; Lymphocytes/immunology ; Lymphocytes/metabolism ; Physical Endurance ; Resistance Training

Objectives: Exercise-induced cellular mobilization might play a role in treatment and prevention of several diseases. However, little is known about the impact of different exercise modalities on immune cell mobilization and clinical cellular inflammation markers. Therefore, the present study aimed to investigate differences between acute endurance exercise (EE) and resistance exercise (RE) on cellular immune alterations.
Methods: Twenty-four healthy men conducted an acute EE (cycling at 60% of peak power output) and RE (five exercise machines at 70% of the one-repetition maximum) session lasting 50 minutes in randomized order. Blood samples were collected before, after and one hour after exercise cessation. Outcomes included counts and proportions of leukocytes, neutrophils (NEUT), lymphocytes (LYM), LYM subsets, CD4/CD8 ratio, and the clinical cellular inflammation markers NEUT/LYM ratio (NLR), platelets/LYM ratio (PLR), and systemic immune inflammation index (SII).
Results: Alterations in all outcomes were revealed except for CD8 ⁺ T cells, CD4/CD8 ratio, NLR, and PLR. EE induced a stronger cellular immune response and provoked alterations in more immune cell populations than RE. SII was altered only after EE.
Conclusion: An acute EE session causes a stronger mobilization of immune cells than RE. Additionally, SII represents an integrative marker to depict immunological alterations.
(© 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)

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Keywords: cellular immune system; endurance exercise; exercise; inflammation; resistance exercise

Date Created: 20200330 Date Completed: 20210617 Latest Revision: 20210617

20221213

10.1111/ejh.13412

32221992