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Stepwise progressive parametric multiple testing procedure with correlated normal test statistics.
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- المؤلفون: Deng X;Deng X; Chang M; Chang M
- المصدر:
Journal of biopharmaceutical statistics [J Biopharm Stat] 2020 May 03; Vol. 30 (3), pp. 550-563. Date of Electronic Publication: 2020 Mar 19.
- نوع النشر :
Journal Article
- اللغة:
English
- معلومة اضافية
- المصدر:
Publisher: Taylor & Francis Country of Publication: England NLM ID: 9200436 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5711 (Electronic) Linking ISSN: 10543406 NLM ISO Abbreviation: J Biopharm Stat Subsets: MEDLINE
- بيانات النشر:
Publication: 2005- : Abingdon, Oxford : Taylor & Francis
Original Publication: New York, N.Y. : Marcel Dekker, c1991-
- الموضوع:
- نبذة مختصرة :
Multiple testing problems are often seen in clinical trials. An appropriate testing procedure should be specified to deal with the potential inflation of type I error rate due to multiplicity. In this article, we propose a stepwise progressive parametric multiple (SPPM) testing procedure, which constructs the testing using the products of all the combinations of local [Formula: see text]-values and the critical values are determined by numerical integrations progressively using the closure principle. We have compared the performance of SPPM to several other procedures, and demonstrate the advantage of SPPM procedure, in terms of power, for the certain situations of multiple testing.
- Contributed Indexing:
Keywords: Group sequential design; multiple primary endpoints; multivariate Normal distribution; stopping boundaries
- الرقم المعرف:
0 (Central Nervous System Stimulants)
R3UK8X3U3D (Modafinil)
- الموضوع:
Date Created: 20200320 Date Completed: 20210708 Latest Revision: 20210708
- الموضوع:
20231215
- الرقم المعرف:
10.1080/10543406.2020.1726369
- الرقم المعرف:
32191556
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