Suicide attempts requiring hospitalization in patients with eating disorders: A retrospective cohort study.

Publisher: Wiley Country of Publication: United States NLM ID: 8111226 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-108X (Electronic) Linking ISSN: 02763478 NLM ISO Abbreviation: Int J Eat Disord Subsets: MEDLINE

Publication: <2005-> : Hoboken, NJ : Wiley
Original Publication: [New York, N.Y. : Van Nostrand Reinhold Co., c1981-

Feeding and Eating Disorders/*complications ; Hospitalization/*trends ; Suicide, Attempted/*psychology; Adolescent ; Adult ; Child ; Cohort Studies ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Young Adult

Objective: Suicide attempts requiring hospitalization are known to be common in patients who are diagnosed with eating disorders. Attempting suicide is a major indicator for those at risk of completed suicide. Both the specific eating disorder diagnosis and the influence of psychiatric comorbidities on suicide attempts requiring hospitalization were investigated, with demographic and socioeconomic variables as confounders, over a 10-year observation period from January 2007 to March 2017.
Methods: Anonymized health-record data from the South London and Maudsley NHS Foundation Trust (SLaM) were retrieved through the Clinical Record Interactive Search (CRIS) data resource; this is linked to national Hospital Episode Statistics (HES) data. These data include all diagnoses for inpatient admissions. Hazard ratios, with 95% confidence intervals (CIs), were calculated from cox regression analyses and the effects of a number of confounders were estimated by performing multivariable analyses.
Results: In total, 4,895 patients were diagnosed with anorexia nervosa (AN), bulimia nervosa (BN), or eating disorder otherwise not specified (EDNOS). Of these, 331 (6.7%) had attempted suicide requiring hospitalization and 21 (0.04%) completed suicide. The eating disorder category associated with the highest risk of a suicide attempt was AN (HR: 1.43, 95%CI: 1.08-1.89, p = .01). The risk was significantly increased further if the patient had a comorbid diagnosis of personality disorder, depression, bipolar affective disorder, and substance misuse.
Discussion: Suicide attempts requiring hospitalization have a high incidence rate among patients with eating disorders, and the risk is significantly increased in AN. Comorbid psychiatric illness and suicidal ideation should be carefully assessed in all eating disorder patients.
(© 2020 Wiley Periodicals, Inc.)

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MC_PC_17214 United Kingdom MRC_ Medical Research Council; MR/T045302/1 United Kingdom MRC_ Medical Research Council; United Kingdom DH_ Department of Health

Keywords: anorexia nervosa; bulimia nervosa; eating disorder; self-harm; suicide; suicide attempt

Date Created: 20200212 Date Completed: 20210125 Latest Revision: 20230913

20231215

10.1002/eat.23240

32043625