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Depressive symptoms, physical symptoms, and health-related quality of life among older adults with HIV.

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  • معلومة اضافية
    • المصدر:
      Publisher: Springer Netherlands Country of Publication: Netherlands NLM ID: 9210257 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2649 (Electronic) Linking ISSN: 09629343 NLM ISO Abbreviation: Qual Life Res Subsets: MEDLINE
    • بيانات النشر:
      Publication: 2005- : Netherlands : Springer Netherlands
      Original Publication: Oxford, UK : Rapid Communications of Oxford, Ltd, c1992-
    • الموضوع:
      Depression/*psychology ; Depressive Disorder/*psychology ; HIV Infections/*psychology ; Quality of Life/*psychology; Aged ; Aging/psychology ; Anti-Retroviral Agents/therapeutic use ; Female ; HIV Infections/drug therapy ; Health Status ; Humans ; Male ; Middle Aged ; New York City ; United States
    • نبذة مختصرة :
      Purpose: In the United States, approximately 45% of persons living with HIV (PLHIV) are ≥ 50 years of age. Many older PLHIV have multi-morbidities that complicate HIV infection and/or interfere with, or are exacerbated by, antiretroviral treatment. Physical health symptoms and psychiatric disorders, particularly depression, can worsen life quality in older PLHIV.
      Methods: This study assessed associations among physical symptoms, indicators of HIV-related health status (i.e., time since diagnosis; ever diagnosed with AIDS; having attained viral suppression), depressive symptoms, and health-related quality of life (HRQoL) in older PLHIV. Regression analyses examined data from 296 PLHIV ≥ 50 years of age living in Cincinnati, OH, Columbus, OH, and New York City.
      Results: Depressive symptoms and physical symptoms, particularly those related to appearance and sexual functioning, most strongly predicted HRQoL. Indicators of HIV health status did not significantly predict HRQoL. Depressive symptoms were a particularly robust predictor of HRQoL, even when accounting for physical health symptoms.
      Conclusion: Findings suggest that symptom management is critical to HRQoL in older PLHIV, and symptoms related to physical appearance and sexual functioning should not be overlooked in this growing population.
    • References:
      HIV Med. 2011 Jan;12(1):22-30. (PMID: 20497251)
      AIDS Patient Care STDS. 2012 Sep;26(9):557-61. (PMID: 22792882)
      AIDS Care. 2017 Nov;29(11):1399-1403. (PMID: 28278562)
      AIDS Patient Care STDS. 2013 Jan;27(1):5-16. (PMID: 23305257)
      Clin Infect Dis. 2010 Jan 15;50(2):255-63. (PMID: 20014949)
      AIDS. 1996 Oct;10(12):1421-7. (PMID: 8902073)
      PLoS One. 2017 Jun 29;12(6):e0179874. (PMID: 28662079)
      Psychiatr Serv. 2000 Jul;51(7):903-7. (PMID: 10875956)
      Psychosom Med. 2008 Jun;70(5):539-45. (PMID: 18519880)
      J Neurovirol. 2017 Jun;23(3):492-500. (PMID: 28321696)
      J Pain Symptom Manage. 2008 Sep;36(3):247-58. (PMID: 18411016)
      Semin Diagn Pathol. 2017 Jul;34(4):384-397. (PMID: 28552209)
      Curr HIV/AIDS Rep. 2011 Dec;8(4):215-22. (PMID: 21822626)
      Psychosomatics. 1992 Fall;33(4):416-27. (PMID: 1461967)
      Qual Life Res. 2010 Oct;19(8):1215-27. (PMID: 20509050)
      AIDS Care. 2017 Dec;29(12):1543-1550. (PMID: 28395528)
      J Behav Med. 2011 Apr;34(2):102-11. (PMID: 20857188)
      Aging Ment Health. 2002 May;6(2):121-8. (PMID: 12028880)
      AIDS Behav. 2013 Nov;17(9):3034-44. (PMID: 23474642)
      J Psychiatr Res. 1982-1983;17(1):37-49. (PMID: 7183759)
      Ann Behav Med. 2003 Oct;26(2):104-23. (PMID: 14534028)
      J Gerontol Nurs. 2007 Mar;33(3):19-27; quiz 38-9. (PMID: 17378188)
      AIDS Patient Care STDS. 2009 Apr;23(4):239-44. (PMID: 19281346)
      AIDS Behav. 2013 Sep 28;18(4):676-685. (PMID: 24077971)
      AIDS. 2017 Jun 19;31(10):1471-1481. (PMID: 28574965)
      AIDS Care. 2013;25(4):451-8. (PMID: 22894702)
      Qual Life Res. 2006 Feb;15(1):173-8. (PMID: 16411042)
      Mol Cell. 2016 Apr 21;62(2):153-155. (PMID: 27105110)
      Qual Life Res. 1996 Aug;5(4):450-63. (PMID: 8840825)
      AIDS Behav. 2010 Apr;14(2):252-62. (PMID: 20013043)
      HIV Med. 2008 Oct;9(9):780-6. (PMID: 18754804)
      AIDS Patient Care STDS. 2010 Jan;24(1):5-13. (PMID: 20095903)
      Am J Psychiatry. 2000 Feb;157(2):248-54. (PMID: 10671395)
      J Antimicrob Chemother. 2008 Mar;61(3):469-73. (PMID: 18174196)
      AIDS Patient Care STDS. 2002 Sep;16(9):413-7. (PMID: 12396693)
      J Pain Symptom Manage. 1999 Oct;18(4):263-70. (PMID: 10534966)
      Curr Opin HIV AIDS. 2014 Jul;9(4):325-31. (PMID: 24824890)
    • Grant Information:
      K23 MH111402 United States MH NIMH NIH HHS; P30 MH062246 United States MH NIMH NIH HHS; K23 MH076671 United States MH NIMH NIH HHS; P30 MH062294 United States MH NIMH NIH HHS; UL1 TR001863 United States TR NCATS NIH HHS; 2017080 United States DDCF Doris Duke Charitable Foundation; K23 DA033858 United States DA NIDA NIH HHS; R01 MH067566 United States MH NIMH NIH HHS; T32 MH019105 United States MH NIMH NIH HHS; R01 MH067568 United States MH NIMH NIH HHS; T32 MH020031 United States MH NIMH NIH HHS; R01-MH067568 United States MH NIMH NIH HHS
    • Contributed Indexing:
      Keywords: Aging; Depression; HIV/AIDS; Physical symptoms; Quality of life
    • الرقم المعرف:
      0 (Anti-Retroviral Agents)
    • الموضوع:
      Date Created: 20190826 Date Completed: 20200203 Latest Revision: 20220129
    • الموضوع:
      20231215
    • الرقم المعرف:
      PMC6868331
    • الرقم المعرف:
      10.1007/s11136-019-02271-0
    • الرقم المعرف:
      31446515