Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request

Mandibular growth in infants with Robin sequence treated with the Tübingen palatal plate.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي
  • معلومة اضافية
    • المصدر:
      Publisher: BioMed Central Country of Publication: England NLM ID: 101245792 Publication Model: Electronic Cited Medium: Internet ISSN: 1746-160X (Electronic) Linking ISSN: 1746160X NLM ISO Abbreviation: Head Face Med Subsets: MEDLINE
    • بيانات النشر:
      Original Publication: [London] : BioMed Central, [2005]-
    • الموضوع:
      Pierre Robin Syndrome*/complications ; Pierre Robin Syndrome*/genetics ; Retrospective Studies* ; Sleep Apnea Syndromes* ; Sleep Apnea, Obstructive*; Humans ; Infant ; Mandible/growth & development ; Mandible/pathology ; Treatment Outcome
    • نبذة مختصرة :
      Background: Robin sequence (RS) is characterized by mandibular retrognathia, glossoptosis and upper airway obstruction. Whether mandibular catch-up growth may occur in RS is yet controversial. Our functional and less invasive treatment including the Tübingen Palatal Plate (TPP), early oral feeding and orofacial stimulation may promote mandibular catch-up growth. We evaluated the effect of the Tübingen Palatal Plate on mandibular growth, expressed by the Jaw index, sleep study results and weight gain in infants admitted with isolated and syndromic RS, born at or referred to our center between 6/2015 and 5/2018.
      Methods: Retrospective analysis of our electronic patient database that included data on jaw index measurements, sleep study results and standard deviation (Z-)scores for weight.
      Results: Of 31 patients referred for RS treatment (22 isolated, 9 syndromic), we had data on the above parameters, determined at admission, discharge and 3 months after discharge, in 20. Jaw index at admission and 3-month follow-up was 8.8 (6.3-11.3) and 2.1 (2.0-4.0), respectively (median (IQR); p < 0.0001). Mixed-obstructive apnea index (MOAI) decreased from 9.7 (4.8-24.2) to 0.0 (0-1.3; p < 0.002). No significant correlation was observed between MOAI and Jaw Index, but MOAI correlated with the Maxillary/Mandibular arch ratio (r = 0.58; p < 0.001). Z-scores for weight were similar at both time points at - 1.34 (- 1.76 - - 0.57) and - 1.50 (- 1.89 - - 0.54), while the proportion of infants requiring nasogastric tube feeding decreased from 84 to 8%. No infant had craniofacial surgery; one with syndromic RS required tracheostomy.
      Conclusion: These longitudinal cohort data suggest that the Tübingen Palatal Plate as used here may alleviate upper airway obstruction by promoting mandibular growth.
      Trial Registration: N.A.
    • References:
      Ann Plast Surg. 1999 Feb;42(2):154-7. (PMID: 10029479)
      Am J Orthod Dentofacial Orthop. 2001 Sep;120(3):280-5. (PMID: 11552127)
      J Pediatr. 2001 Oct;139(4):588-90. (PMID: 11598609)
      Am J Orthod. 1979 Dec;76(6):593-611. (PMID: 117715)
      Cleft Palate Craniofac J. 2003 Mar;40(2):131-43. (PMID: 12605518)
      Cleft Palate Craniofac J. 2003 Jul;40(4):373-96. (PMID: 12846603)
      AMA Am J Dis Child. 1954 Jul;88(1):29-42. (PMID: 13170810)
      Scand J Plast Reconstr Surg Hand Surg. 1992;26(2):177-83. (PMID: 1411346)
      Cleft Palate Craniofac J. 2003 Nov;40(6):618-23. (PMID: 14577814)
      Cleft Palate Craniofac J. 2004 Jan;41(1):47-52. (PMID: 14697070)
      Cleft Palate Craniofac J. 2006 Mar;43(2):160-7. (PMID: 16526921)
      Angle Orthod. 2006 Sep;76(5):898-908. (PMID: 17029529)
      Cleft Palate Craniofac J. 1991 Oct;28(4):425-34. (PMID: 1742314)
      J Pediatr. 2007 Aug;151(2):145-9. (PMID: 17643765)
      J Oral Maxillofac Surg. 2009 Nov;67(11):2323-31. (PMID: 19837298)
      J Craniofac Surg. 2009 Nov;20(6):2055-60. (PMID: 19881369)
      Cleft Palate Craniofac J. 2011 May;48(3):331-6. (PMID: 20180703)
      Am J Orthod Dentofacial Orthop. 2010 Jun;137(6):763-74. (PMID: 20685531)
      Pediatrics. 2011 May;127(5):936-48. (PMID: 21464188)
      J Pediatr. 2011 Dec;159(6):887-92. (PMID: 21885059)
      J Pediatr. 2012 Apr;160(4):645-650.e2. (PMID: 22048048)
      Arch Dis Child Fetal Neonatal Ed. 2014 Nov;99(6):F491-4. (PMID: 25164557)
      Int J Pediatr Otorhinolaryngol. 2015 Apr;79(4):451-64. (PMID: 25704848)
      J Craniomaxillofac Surg. 2015 Oct;43(8):1626-31. (PMID: 26315273)
      Arch Dis Child Fetal Neonatal Ed. 2017 Mar;102(2):F142-F146. (PMID: 27435577)
      Ann Maxillofac Surg. 2016 Jan-Jun;6(1):44-9. (PMID: 27563606)
      Orphanet J Rare Dis. 2017 Mar 9;12(1):46. (PMID: 28274235)
      Head Face Med. 2017 Mar 30;13(1):4. (PMID: 28356131)
      Cleft Palate Craniofac J. 2019 Feb;56(2):168-176. (PMID: 29727222)
      Cleft Palate Craniofac J. 1997 May;34(3):240-1. (PMID: 9167075)
      Stat Med. 1998 Feb 28;17(4):407-29. (PMID: 9496720)
    • الموضوع:
      Date Created: 20190624 Date Completed: 20191202 Latest Revision: 20200225
    • الموضوع:
      20250114
    • الرقم المعرف:
      PMC6588871
    • الرقم المعرف:
      10.1186/s13005-019-0200-1
    • الرقم المعرف:
      31228944