Microneedle fractional radiofrequency treatment of facial photoageing as assessed in a split-face model.

Publisher: Oxford University Press Country of Publication: England NLM ID: 7606847 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2230 (Electronic) Linking ISSN: 03076938 NLM ISO Abbreviation: Clin Exp Dermatol Subsets: MEDLINE

Publication: 2023- : Oxford : Oxford University Press
Original Publication: Oxford : Blackwell Scientific Publications.

Face/*physiopathology ; Pulsed Radiofrequency Treatment/*instrumentation ; Skin/*radiation effects ; Skin Aging/*radiation effects; Adult ; China/epidemiology ; Cosmetic Techniques/instrumentation ; Erythema/etiology ; Erythema/pathology ; Female ; Humans ; Imaging, Three-Dimensional/methods ; Melanins/radiation effects ; Middle Aged ; Needles ; Patient Satisfaction ; Pulsed Radiofrequency Treatment/adverse effects ; Skin/metabolism ; Skin/pathology ; Skin Aging/pathology ; Treatment Outcome

Background: A new therapeutic device passes radiofrequency energy through microneedles to targeted tissue. Three-dimensional photography may be useful for evaluating the clinical efficacy of microneedle fractional radiofrequency (MFR) used on the appearance of rhytids and to improve facial laxity.
Aim: To evaluate the efficacy and safety of MFR in the treatment of facial photoageing.
Methods: In total, participants with facial photoageing were enrolled in the study. All volunteers were randomized to receive split-face treatments with MFR 2 months apart. The participants self-evaluated at baseline, Days 1-7, and Months 1 and 3 after the final treatment. Objective evaluation was provided by a three-dimensional in vivo imaging system. In addition, skin melanin index, erythema index, immediate reactions, healing times and other adverse effects were evaluated.
Results: Compared with the untreated side, the treated side of most participants improved, based on clinical assessments at the 1- and 3-month follow-up visits after treatment. Both objective and participative assessments were satisfactory. The participants demonstrated a decrease of roughness parameter (Sa) value at each follow-up visit. Compared with pretreatment value, Sa decreased significantly at Months 1 and 3 on the treated side (P < 0.05). Minimal and reversible adverse effects and rapid healing were recorded.
Conclusions: MFR appears to be an excellent treatment for photodamaged facial skin in Chinese patients.
(© 2019 British Association of Dermatologists.)

0 (Melanins)

Date Created: 20190203 Date Completed: 20200106 Latest Revision: 20200106

20240628

10.1111/ced.13924

30710383