Agreement of child and parent-proxy reported health-related quality of life in children with mental disorder.

Publisher: Springer Netherlands Country of Publication: Netherlands NLM ID: 9210257 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2649 (Electronic) Linking ISSN: 09629343 NLM ISO Abbreviation: Qual Life Res Subsets: MEDLINE

Publication: 2005- : Netherlands : Springer Netherlands
Original Publication: Oxford, UK : Rapid Communications of Oxford, Ltd, c1992-

Anxiety/*psychology ; Depression/*psychology ; Parents/*psychology ; Psychotic Disorders/*diagnosis ; Psychotic Disorders/*psychology ; Quality of Life/*psychology; Adolescent ; Child ; Child, Preschool ; Female ; Humans ; Male ; Proxy ; Psychotic Disorders/pathology

Purpose: The purpose of the study was to test whether elevated levels of depressive and anxiety symptoms affect parent-proxy reports of health-related quality of life (HRQL) of children with mental disorder.
Methods: A sample of 114 children, who screened positive for mental disorder using the Mini International Neuropsychiatric Interview were studied. Parents' depressive symptoms were measured using the Center for Epidemiological Studies Depression Scale (CES-D) and anxiety symptoms using the State Trait Anxiety Inventory (STAI). To examine whether parental psychopathology moderated their reports of child HRQL (using the KIDSCREEN-27), a series of multiple regression analyses with product-term interactions were conducted.
Results: Significant interactions were found for the moderating effect of parental depressive [β = 0.025 (0.007, 0.042)] and anxiety symptoms [β = 0.033 (0.011, 0.054)] on the domain of child social support and peers relations, as well as for the moderating effect of parental levels of depression on parent proxy child physical well-being [β = - 0.017 (- 0.031, - 0.003)]. Parents with elevated levels of depressive or anxiety symptoms reported lower scores for those domains of child HRQL.
Conclusions: Symptoms of depression and anxiety in parents influence their reports of the HRQL of their children with mental disorder, particularly in the areas of physical well-being and social support and peers. Given the importance of patient-reported outcomes in the assessment and monitoring of children with chronic conditions, including HRQL, health professionals caring for children with mental disorder should be aware of how parental psychopathology contributes to informant bias. Future research examining why psychopathology influences parental reports of child HRQL is warranted.

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133645 Canada Canadian Institutes of Health Research; 14363 Hamilton Health Sciences

Keywords: Anxiety; Depression; Informant bias; Mental disorder; Proxy report

Date Created: 20181018 Date Completed: 20190328 Latest Revision: 20200225

20240829

10.1007/s11136-018-2026-x

30328009