Mapping Histoplasma capsulatum Exposure, United States.

Publisher: National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC) Country of Publication: United States NLM ID: 9508155 Publication Model: Print Cited Medium: Internet ISSN: 1080-6059 (Electronic) Linking ISSN: 10806040 NLM ISO Abbreviation: Emerg Infect Dis Subsets: MEDLINE

Original Publication: Atlanta, GA : National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC), [1995-

Environmental Exposure*; Histoplasma/*classification ; Histoplasmosis/*epidemiology ; Histoplasmosis/*microbiology; Area Under Curve ; Geography, Medical ; Humans ; Incidence ; Population Surveillance ; Prevalence ; Soil/chemistry ; Soil Microbiology ; United States/epidemiology

Maps of Histoplasma capsulatum infection prevalence were created 50 years ago; since then, the environment, climate, and anthropogenic land use have changed drastically. Recent outbreaks of acute disease in Montana and Nebraska, USA, suggest shifts in geographic distribution, necessitating updated prevalence maps. To create a weighted overlay geographic suitability model for Histoplasma, we used a geographic information system to combine satellite imagery integrating land cover use (70%), distance to water (20%), and soil pH (10%). We used logistic regression modeling to compare our map with state-level histoplasmosis incidence data from a 5% sample from the Centers for Medicare and Medicaid Services. When compared with the state-based Centers data, the predictive accuracy of the suitability score-predicted states with high and mid-to-high histoplasmosis incidence was moderate. Preferred soil environments for Histoplasma have migrated into the upper Missouri River basin. Suitability score mapping may be applicable to other geographically specific infectious vectors.

MMWR Morb Mortal Wkly Rep. 2013 Oct 25;62(42):834-7. (PMID: 24153314)
Semin Respir Crit Care Med. 2011 Dec;32(6):735-44. (PMID: 22167401)
Am Rev Respir Dis. 1969 Apr;99(4):Suppl:1-132. (PMID: 5767603)
Emerg Infect Dis. 2015 Jun;21(6):1071-2. (PMID: 25989199)
Infect Dis Clin North Am. 2016 Mar;30(1):207-27. (PMID: 26897068)
Ann Thorac Surg. 2011 Aug;92(2):428-32; discussion 433. (PMID: 21592456)
Emerg Infect Dis. 2016 Mar;22(3):370-8. (PMID: 26890817)
Mycopathol Mycol Appl. 1967 Nov 13;33(2):145-56. (PMID: 5585327)
Curr Trop Med Rep. 2015 Jun 1;2(2):70-80. (PMID: 26279969)
Emerg Infect Dis. 2011 Sep;17(9):1664-9. (PMID: 21888792)
Am J Trop Med Hyg. 1951 Nov;31(6):742-52. (PMID: 14894759)
Emerg Infect Dis. 2017 Mar;24(3):425-431. (PMID: 29460731)
N Engl J Med. 2011 Aug 4;365(5):395-409. (PMID: 21714641)
Mycopathol Mycol Appl. 1970;41(1):167-76. (PMID: 5535367)
J Infect Dis. 1952 Jan-Feb;90(1):67-70. (PMID: 14888969)
MMWR Morb Mortal Wkly Rep. 2004 Nov 5;53(43):1020-2. (PMID: 15525901)
Lung Cancer. 2002 Jun;36(3):297-301. (PMID: 12009241)
JAMA. 2014 Sep 24;312(12):1227-36. (PMID: 25247519)

K07 CA172294 United States CA NCI NIH HHS

Keywords: Histoplasma capsulatum; United States; endemic mycoses; fungi; histoplasmosis; mapping; suitability score

0 (Soil)

Date Created: 20180919 Date Completed: 20190513 Latest Revision: 20190513

20231215

PMC6154167

10.3201/eid2410.180032

30226187