Chronic ulcerative stomatitis: Case series of an under-recognized entity.

Publisher: Wiley Country of Publication: United States NLM ID: 0425124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0560 (Electronic) Linking ISSN: 03036987 NLM ISO Abbreviation: J Cutan Pathol Subsets: MEDLINE

Publication: Malden, MA : Wiley
Original Publication: Copenhagen, Blackwell Munksgaard.

Gingivitis, Necrotizing Ulcerative*/metabolism ; Gingivitis, Necrotizing Ulcerative*/pathology ; Lichen Planus, Oral*/metabolism ; Lichen Planus, Oral*/pathology; Aged ; Aged, 80 and over ; Chronic Disease ; Female ; Humans ; Male ; Middle Aged

Chronic ulcerative stomatitis (CUS) is a mucocutaneous condition characterized by chronic relapsing and remitting oral ulcers and erosions. This condition remains under-recognized among dermatopathologists, possibly because of common misdiagnosis as oral erosive lichen planus (LP). We report five cases of CUS in order to raise awareness of this uncommon condition. All patients presented with desquamative gingivitis and/or oral erosions, with biopsies showing lichenoid mucositis and epithelial nuclear IgG deposition on direct immunofluorescence. Recognition of the characteristic direct immunofluorescence findings allows for distinction of chronic ulcerative stomatitis from oral LP and appropriate therapy.
(© 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)

Keywords: antinuclear antibody; chronic ulcerative stomatitis; direct immunofluorescence; lichen planus

Date Created: 20180831 Date Completed: 20190123 Latest Revision: 20190123

20250114

10.1111/cup.13347

30159907