Item request has been placed!
×
Item request cannot be made.
×
![loading](/sites/all/modules/hf_eds/images/loading.gif)
Processing Request
[Accidents in patients under anticoagulant therapy in the Department of Cardiology at the Yalgado Ouedraogo Teaching Hospital, Ouagadougou (Burkina Faso)].
Item request has been placed!
×
Item request cannot be made.
×
![loading](/sites/all/modules/hf_eds/images/loading.gif)
Processing Request
- معلومة اضافية
- Transliterated Title:
Les accidents du traitement anticoagulant dans le Service de Cardiologie du Centre Hospitalier Universitaire Yalgado Ouedraogo de Ouagadougou (Burkina Faso).
- المصدر:
Publisher: African Field Epidemiology Network Country of Publication: Uganda NLM ID: 101517926 Publication Model: eCollection Cited Medium: Internet ISSN: 1937-8688 (Electronic) NLM ISO Abbreviation: Pan Afr Med J Subsets: MEDLINE
- بيانات النشر:
Original Publication: Kampala, Uganda : African Field Epidemiology Network
- الموضوع:
- نبذة مختصرة :
This study aimed to evaluate the profile of patients hospitalized for anticoagulant-induced hemorrhage. We conducted a retrospective, descriptive study within the Department of Cardiology at the Yalgado Ouedraogo Teaching Hospital, in Ouagadougou, over a period of 2 years from 1 January 2007 to 31 December 2008. All hospitalized patients with anticoagulant-induced hemorrhage were included in the study. The average age of patients was 49,31 ± 17,68 years, the sex-ratio was 2,17. Myocardial infarction was the first indication for anticoagulant treatment, with a rate of 21.05%. Anti vitamin K (AVK) was associated with hemorrhage in 63,16% (n=12) of patients versus 36,84% (n=7) of patients treated with low molecular weight heparins (LMWH); 10 patients had major hemorrhage while nine patients had minor hemorrhage. The average duration of Anti vitamin K (AVK) treatment was 16 ± 58 weeks. Hemorrhage in the digestive tract was the most frequent symptom (31,58%) and, in 89,47% of patients, treatment was associated with platelet aggregation. Treatment of hemorrhagic accident was based on definitive cessation of anticoagulant therapy in 73,68% of patients. Four patients (21.05%) died. The inaccessibility to antidotes such as protamine sulphate and PPSD (Prothrombin, Proconvertine, Stuart factor, and anti-haemophilia B factor) constitutes a real obstacle to adequate treatment for complications; a better education of patients receiving these drugs would be the most important preventive measure, because more than 50% of these accidents are preventable.
- References:
Lancet. 1996 Aug 17;348(9025):423-8. (PMID: 8709780)
Ann Cardiol Angeiol (Paris). 2006 Jan;55(1):22-6. (PMID: 16457032)
Am J Med. 1993 Sep;95(3):315-28. (PMID: 8368229)
J Mal Vasc. 1999 Jun;24(3):202-7. (PMID: 10467530)
J Intern Med. 1991 Apr;229(4):351-5. (PMID: 2026988)
Am J Med. 1989 Aug;87(2):144-52. (PMID: 2787958)
J Mal Vasc. 1994;19(2):98-102. (PMID: 8077870)
Tunis Med. 2009 Nov;87(11):763-9. (PMID: 20209835)
Am J Hematol. 2000 Apr;63(4):192-6. (PMID: 10706762)
Ann Intern Med. 1993 Apr 1;118(7):511-20. (PMID: 8280198)
BMJ. 2000 Apr 15;320(7241):1036. (PMID: 10764362)
BMJ. 2004 Jul 3;329(7456):15-9. (PMID: 15231615)
Arch Mal Coeur Vaiss. 1994 Dec;87(12):1715-9. (PMID: 7786112)
Thromb Haemost. 1996 Nov;76(5):682-8. (PMID: 8950773)
Am J Med. 1997 Jul;103(1):11-7. (PMID: 9236480)
Presse Med. 2003 Jun 14;32(21):972-7. (PMID: 12876525)
Pan Afr Med J. 2012;11:24. (PMID: 22514758)
Rev Med Interne. 2009 Jul;30(7):567-72. (PMID: 19299042)
- Contributed Indexing:
Keywords: Anticoagulant; hemorrhage; venous thrombosis
- الرقم المعرف:
0 (Anticoagulants)
0 (Antidotes)
0 (Heparin, Low-Molecular-Weight)
12001-79-5 (Vitamin K)
- الموضوع:
Date Created: 20180728 Date Completed: 20180827 Latest Revision: 20220330
- الموضوع:
20240628
- الرقم المعرف:
PMC6057581
- الرقم المعرف:
10.11604/pamj.2018.29.135.10650
- الرقم المعرف:
30050599
No Comments.