Nanomotors for Nucleic Acid, Proteins, Pollutants and Cells Detection.

Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

Original Publication: Basel, Switzerland : MDPI, [2000-

Biosensing Techniques*; Biomedical Research/*methods ; Molecular Motor Proteins/*chemistry ; Nanostructures/*chemistry ; Nanotechnology/*methods; Aptamers, Nucleotide/chemistry ; Biomedical Research/instrumentation ; Drug Delivery Systems/instrumentation ; Drug Delivery Systems/methods ; Environmental Pollutants/analysis ; Environmental Pollutants/chemistry ; Humans ; Interdisciplinary Communication ; Molecular Motor Proteins/metabolism ; Nanostructures/ultrastructure ; Nanotechnology/instrumentation ; Nucleic Acids/analysis ; Nucleic Acids/chemistry

The development of nanomachines able to operate at the nanoscale, performing complex tasks such as drug delivery, precision surgery, or cell detection, constitutes one of the most important challenges in nanotechnology. The principles that rule the nanoscale are completely different from the ones which govern the macroscopic world and, therefore, the collaboration of scientists with expertise in different fields is required for the effective fabrication of these tiny machines. In this review, the most recent advances carried out in the synthesis and application of nanomachines for diagnosis applications will be presented in order to provide a picture of their potential in the detection of important biomolecules or pathogens in a selective and controlled manner.

Angew Chem Int Ed Engl. 2011 Apr 26;50(18):4161-4. (PMID: 21472835)
Nano Lett. 2016 Jan 13;16(1):555-61. (PMID: 26699202)
Phys Rev Lett. 2005 Jun 10;94(22):220801. (PMID: 16090376)
ACS Nano. 2013 Oct 22;7(10):9232-40. (PMID: 23971861)
ACS Nano. 2015 Jul 28;9(7):6756-64. (PMID: 26035455)
Nat Nanotechnol. 2009 Dec;4(12):855-60. (PMID: 19915570)
ACS Nano. 2016 Jun 28;10(6):5619-34. (PMID: 27219742)
Phys Rev Lett. 2007 Jul 27;99(4):048102. (PMID: 17678409)
Anal Chem. 2014 May 6;86(9):4501-7. (PMID: 24731140)
N Engl J Med. 2004 Aug 19;351(8):781-91. (PMID: 15317891)
Angew Chem Int Ed Engl. 2013 Jul 1;52(27):7000-3. (PMID: 23703837)
Nano Lett. 2016 Apr 13;16(4):2860-6. (PMID: 26998896)
Small. 2010 Dec 6;6(23):2741-7. (PMID: 20979242)
J Am Chem Soc. 2009 Sep 2;131(34):12082-3. (PMID: 19670862)
Small. 2012 Feb 6;8(3):460-7. (PMID: 22174121)
Nat Commun. 2018 Jan 31;9(1):453. (PMID: 29386522)
Sci Robot. 2017 Mar 15;2(4):. (PMID: 31552379)
Adv Mater. 2013 Dec 3;25(45):6581-8. (PMID: 23996782)
Anal Chem. 2017 Oct 17;89(20):10850-10857. (PMID: 28889736)
Chem Commun (Camb). 2015 Mar 21;51(23):4782-4. (PMID: 25697823)
Nanoscale. 2010 Sep;2(9):1643-9. (PMID: 20680201)
Adv Healthc Mater. 2015 Jan 28;4(2):209-14. (PMID: 24986087)
Nanoscale. 2015 May 21;7(19):8684-8. (PMID: 25902947)
Nat Commun. 2010 Jul 13;1:36. (PMID: 20975708)
Analyst. 2015 Mar 7;140(5):1421-7. (PMID: 25622851)
Anal Chem. 2011 Oct 15;83(20):7962-9. (PMID: 21888314)
J Chem Phys. 2013 Jan 14;138(2):020901. (PMID: 23320656)
Nat Rev Drug Discov. 2010 Jul;9(7):537-50. (PMID: 20592747)
Nanoscale. 2014 Jul 7;6(13):7175-82. (PMID: 24752489)
J Am Chem Soc. 2012 Sep 19;134(37):15217-20. (PMID: 22947052)
Micromachines (Basel). 2018 Feb 13;9(2):. (PMID: 30393354)
Nano Lett. 2011 May 11;11(5):2083-7. (PMID: 21491941)
J Am Chem Soc. 2008 Jul 9;130(27):8633-41. (PMID: 18557614)
Biotechnology (N Y). 1993 Sep;11(9):1026-30. (PMID: 7764001)
Anal Chem. 2014 Dec 2;86(23):11913-8. (PMID: 25369729)
Anal Chem. 2015 Dec 15;87(24):12380-6. (PMID: 26595193)
Nano Lett. 2012 Jan 11;12(1):396-401. (PMID: 22136558)
Nano Lett. 2008 May;8(5):1271-6. (PMID: 18416540)
Chem Commun (Camb). 2016 Feb 25;52(16):3360-3. (PMID: 26824395)
Nanoscale. 2013 Feb 21;5(4):1325-31. (PMID: 23123833)
Small. 2012 Jul 9;8(13):2053-9. (PMID: 22511610)
Lab Chip. 2014 Sep 21;14(18):3505-9. (PMID: 25017813)
Chemistry. 2014 Apr 7;20(15):4292-6. (PMID: 24652757)
Small. 2018 Jan;14(3):. (PMID: 29171716)
ACS Nano. 2015 Sep 22;9(9):9252-9. (PMID: 26308491)
ACS Nano. 2012 Feb 28;6(2):1751-6. (PMID: 22233271)
J Am Chem Soc. 2010 Oct 20;132(41):14403-5. (PMID: 20879711)
J Am Chem Soc. 2006 Nov 22;128(46):14881-8. (PMID: 17105298)

694160 International ERC_ European Research Council

Keywords: biomolecule detection; nanomotors; self-propelled nanosensors

0 (Aptamers, Nucleotide)
0 (Environmental Pollutants)
0 (Molecular Motor Proteins)
0 (Nucleic Acids)

Date Created: 20180526 Date Completed: 20180926 Latest Revision: 20230926

20250114

PMC6032312

10.3390/ijms19061579

29799489