Augmentation of respiratory muscle activities in preterm infants with feeding desaturation.

Publisher: Korean Pediatric Society Country of Publication: Korea (South) NLM ID: 101215374 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1738-1061 (Print) Linking ISSN: 17381061 NLM ISO Abbreviation: Korean J Pediatr Subsets: PubMed not MEDLINE

Original Publication: Sŏul : Korean Pediatric Society, c2004-c2019.

Purpose: Frequent desaturation due to immature incoordination of suck-swallow-breathing in preterm infants can influence multiple organs such as the heart, lungs, and brain, which can then affect growth and development. Most notably in preterm infants, feeding desaturation may even affect pulmonary function during gavage feeding. Because respiratory muscle activities may reflect the work required during respiration, we evaluated the differences in these activities between full-term and preterm infants with feeding desaturation, and investigated the correlations with clinical variables.
Methods: Nineteen preterm infants with feeding desaturation (group 1) and 19 age-matched full-term infants (group 2) were evaluated. Oromotor function was evaluated using video recording. The root-mean-squre (RMS) envelope of the electromyography signal was calculated to quantify the activities of muscles involved in respiration. The differences in RMS between both groups and the correlation with clinical variables including gestational age (GA), birth weight (BW), and Apgar scores (AS) at 1 and 5 minutes after birth were evaluated.
Results: The RMS values of the diaphragm (RMS-D) and rectus abdominis (RMS-R) were significantly greater in group 1 compared to group 2, and the 1- and 5-min AS were significantly lower in group 1 compared to group 2. RMS-D and RMS-R were inversely correlated with GA, BW, 1- and 5-min AS in all infants.
Conclusion: This study showed that respiratory muscle activities were augmented during feeding in preterm infants compared to full-term infants. Additionally, respiratory muscle activities were inversely correlated with all clinical variables.
Competing Interests: Conflicts of interest: No potential conflict of interest relevant to this article was reported.

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Keywords: Feeding desaturation; Preterm infants; Respiratory muscles

Date Created: 20180410 Latest Revision: 20220316

20221213

PMC5876508

10.3345/kjp.2018.61.3.78

29628967