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Waiting list outcome of Peld/Meld exceptions: A single-center experience in Argentina.

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اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي
  • معلومة اضافية
    • المصدر:
      Publisher: Munksgaard Country of Publication: Denmark NLM ID: 9802574 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1399-3046 (Electronic) Linking ISSN: 13973142 NLM ISO Abbreviation: Pediatr Transplant Subsets: MEDLINE
    • بيانات النشر:
      Original Publication: Copenhagen ; Malden, MA : Munksgaard, c1997-
    • الموضوع:
      Liver Transplantation* ; Patient Selection* ; Severity of Illness Index*; End Stage Liver Disease/*diagnosis ; Health Care Rationing/*methods ; Waiting Lists/*mortality; Adolescent ; Argentina ; Child ; Child, Preschool ; End Stage Liver Disease/mortality ; End Stage Liver Disease/surgery ; Female ; Health Policy ; Humans ; Infant ; Infant, Newborn ; Male ; Retrospective Studies
    • نبذة مختصرة :
      As PELD/MELD-based allocation policy was adopted in Argentina in 2005, a system of exception points has been in place in order to award increased waitlist priority to those patients whose severity of illness is not captured by the PELD/MELD score. We aimed to investigate the WL outcome of patients with granted PELD/MELD exceptions. A retrospective cohort study was conducted in children under 18 years old. WL outcomes were evaluated using univariable analysis. From 07/2005 to 01/2014, 408 children were listed for LT. There were 304 classified by calculated PELD/MELD. During this time, 85 (30%) PELD/MELD exceptions were granted. In this cohort, 89.4% (76 of 85) were transplanted and 7.1% (6 of 85) died while on the WL. The remaining 3 pts (3.5%) were removed from the WL due to other causes. We compared the impact of PELD/MELD exceptions in those 85 patients to outcomes in 87 non-exception patients with PELD/MELD ≥19 points. Patients with the exception had significantly better access to WL and lower WL mortality. Our data suggest that children listed by PELD/MELD exceptions had an advantage compared to children with CLD with equivalent PELD/MELD listing priorities.
      (© 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)
    • Contributed Indexing:
      Keywords: exception scores; liver transplantation; pediatric liver allocation
    • الموضوع:
      Date Created: 20180104 Date Completed: 20180905 Latest Revision: 20180905
    • الموضوع:
      20231215
    • الرقم المعرف:
      10.1111/petr.13107
    • الرقم المعرف:
      29297966