Depression and anxiety correlate with disease-related characteristics and quality of life in Chinese patients with gout: a case-control study.

Publisher: Routledge Country of Publication: England NLM ID: 9604099 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1465-3966 (Electronic) Linking ISSN: 13548506 NLM ISO Abbreviation: Psychol Health Med Subsets: MEDLINE

Publication: Abingdon, Oxon : Routledge
Original Publication: Abingdon, Oxfordshire, UK ; Cambridge, MA : Carfax, c1996-

Anxiety Disorders/*psychology ; Asian People/*psychology ; Depressive Disorder/*psychology ; Gout/*psychology ; Quality of Life/*psychology; Adult ; Aged ; Anxiety Disorders/diagnosis ; Anxiety Disorders/epidemiology ; Asian People/statistics & numerical data ; Case-Control Studies ; China ; Correlation of Data ; Cross-Sectional Studies ; Depressive Disorder/diagnosis ; Depressive Disorder/epidemiology ; Female ; Gout/epidemiology ; Humans ; Male ; Middle Aged ; Risk Factors ; Surveys and Questionnaires

This study aims to evaluate the prevalence of depression and anxiety and investigate the potential risk factors for depression and anxiety in Chinese gout patients. A self-report survey was administered to 226 gout patients and 232 age- and gender-matched healthy individuals. Patients were asked to complete a set of standardized self-report questionnaires. Univariate and mutiple regression were used to analyze the data. We found 15.0% of gout patients had depression, and 5.3% had anxiety. After adjusted demographic variables, the prevalence of depression was significantly higher than the healthy controls (6.0%). There were significant correlations among education, total pain, disease duration, stage of gout, functional disability, number of tophi, number of flares/last year, presence of tender joints, nephropathy comorbidity, health-related quality of life (HRQoL), and psychological status. Meanwhile, logistic regression analysis identified number of tophi, functional disability, and mental component summary (MCS) as predictors of depression in gout patients. Education and MCS were significantly accounted for anxiety. In summary, the prevalence of depressive symptoms among gout patients was higher than healthy individuals. Education, disability, tophi and HRQoL were important risk factors linked to depression/anxiety in Chinese gout population.

Keywords: Gout; anxiety; depression; health-related quality of life

Date Created: 20170926 Date Completed: 20190211 Latest Revision: 20221207

20231215

10.1080/13548506.2017.1378819

28942667