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Investigation of the Etiology of Central Serous Chorioretinopathy Using En-Face Optical Coherence Tomography and Indocyanine Green Angiography.

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  • المؤلفون: Shinojima A;Shinojima A; Fujita K; Mori R; Kawamura A; Yuzawa M; Yasukawa T
  • المصدر:
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde [Ophthalmologica] 2016; Vol. 236 (2), pp. 100-7. Date of Electronic Publication: 2016 Aug 18.
  • نوع النشر :
    Journal Article
  • اللغة:
    English
  • معلومة اضافية
    • المصدر:
      Publisher: Karger Country of Publication: Switzerland NLM ID: 0054655 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1423-0267 (Electronic) Linking ISSN: 00303755 NLM ISO Abbreviation: Ophthalmologica Subsets: MEDLINE
    • بيانات النشر:
      Publication: Basel : Karger
      Original Publication: Basel.
    • الموضوع:
      Visual Acuity*; Central Serous Chorioretinopathy/*diagnosis ; Choroid/*pathology ; Fluorescein Angiography/*methods ; Indocyanine Green/*pharmacology ; Retinal Pigment Epithelium/*pathology ; Tomography, Optical Coherence/*methods; Adult ; Aged ; Central Serous Chorioretinopathy/etiology ; Central Serous Chorioretinopathy/physiopathology ; Coloring Agents/pharmacology ; Female ; Follow-Up Studies ; Fundus Oculi ; Humans ; Male ; Middle Aged ; Retrospective Studies
    • نبذة مختصرة :
      Purpose: To identify locations of hypofluorescent lesions on late-phase indocyanine green angiography (ICGA) in patients with central serous chorioretinopathy (CSC) using en-face optical coherence tomography (OCT).
      Procedures: We retrospectively studied 25 consecutive untreated CSC patients, using swept-source OCT and ICGA. En-face swept-source OCT images were automatically segmented and flattened with Bruch's membrane (BrM). We compared the sizes of hyperreflective areas in the 25 CSC and 25 contralateral eyes on en-face images and hypofluorescent areas on ICGA after 30 min.
      Results: All 25 CSC eyes and 13 contralateral eyes showed abnormal hypofluorescent areas on late-phase ICGA and hyperreflective areas on en-face OCT from BrM to the choriocapillaris, and these findings correlated with the abnormal areas (r = 0.9988; p < 0.001).
      Conclusions: In CSC patients, we detected abnormal hypofluorescence on ICGA in the late phase, which corresponded to abnormal hyperreflective areas from BrM to the choriocapillaris level in en-face images.
      (© 2016 S. Karger AG, Basel.)
    • الرقم المعرف:
      0 (Coloring Agents)
      IX6J1063HV (Indocyanine Green)
    • الموضوع:
      Date Created: 20160818 Date Completed: 20170131 Latest Revision: 20170131
    • الموضوع:
      20221213
    • الرقم المعرف:
      10.1159/000448342
    • الرقم المعرف:
      27532435