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Incorporation of poison center services in a state-wide overdose education and naloxone distribution program.

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  • معلومة اضافية
    • المصدر:
      Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 9208821 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0391 (Electronic) Linking ISSN: 10550496 NLM ISO Abbreviation: Am J Addict Subsets: MEDLINE
    • بيانات النشر:
      Publication: Oxford : Wiley-Blackwell
      Original Publication: Washington, DC : American Psychiatric Press, c1992-
    • الموضوع:
      Analgesics, Opioid/*poisoning ; Drug Overdose/*prevention & control ; Naloxone/*therapeutic use ; Narcotic Antagonists/*therapeutic use ; Poison Control Centers/*organization & administration ; Preventive Health Services/*organization & administration ; Substance Abuse Treatment Centers/*organization & administration; Adolescent ; Adult ; Aged ; Drug Overdose/drug therapy ; Female ; Humans ; Male ; Maryland ; Middle Aged ; Preventive Health Services/methods ; Program Evaluation ; Retrospective Studies ; Substance Abuse Treatment Centers/methods ; Treatment Outcome ; Young Adult
    • نبذة مختصرة :
      Background: To help curb the opioid overdose epidemic, many states are implementing overdose education and naloxone distribution (OEND) programs. Few evaluations of these programs exist. Maryland's OEND program incorporated the services of the poison center. It asked bystanders to call the poison center within 2 hours of administration of naloxone. Bystanders included law enforcement (LE).
      Objective: Description of the initial experience with this unique OEND program component.
      Methods: Retrospective case series of all cases of bystander-administered naloxone reported to the Maryland Poison Center over 16 months. Cases were followed to final outcome, for example, hospital discharge or death. Indications for naloxone included suspected opioid exposure and unresponsiveness, respiratory depression, or cyanosis. Naloxone response was defined as person's ability to breathe, talk, or walk within minutes of administration.
      Results: Seventy-eight cases of bystander-administered naloxone were reported. Positive response to naloxone was observed in 75.6% of overall cases. Response rates were 86.1% and 70.9% for suspected exposures to heroin and prescription opioids, respectively. Two individuals failed to respond to naloxone and died.
      Discussion: Naloxone response rates were higher and admission to the intensive care unit rates were lower in heroin overdoses than prescription opioid overdoses.
      Conclusions: This retrospective case series of 78 cases of bystander-administered naloxone reports a 75.6% overall rate of reversal.
      Scientific Significance: The findings of this study may be more generalizable. Incorporation of poison center services facilitated the capture of more timely data not usually available to OEND programs. (Am J Addict 2016;25:301-306).
      (© 2016 American Academy of Addiction Psychiatry.)
    • الرقم المعرف:
      0 (Analgesics, Opioid)
      0 (Narcotic Antagonists)
      36B82AMQ7N (Naloxone)
    • الموضوع:
      Date Created: 20160525 Date Completed: 20171102 Latest Revision: 20191210
    • الموضوع:
      20231215
    • الرقم المعرف:
      10.1111/ajad.12384
    • الرقم المعرف:
      27219823