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The association between medically unexplained physical symptoms and health care use over two years and the influence of depressive and anxiety disorders and personality traits: a longitudinal study.

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  • معلومة اضافية
    • المصدر:
      Publisher: BioMed Central Country of Publication: England NLM ID: 101088677 Publication Model: Electronic Cited Medium: Internet ISSN: 1472-6963 (Electronic) Linking ISSN: 14726963 NLM ISO Abbreviation: BMC Health Serv Res Subsets: MEDLINE
    • بيانات النشر:
      Original Publication: London : BioMed Central, [2001-
    • الموضوع:
      Anxiety Disorders/*psychology ; Depressive Disorder/*psychology; Adolescent ; Adult ; Aged ; Chronic Disease ; Female ; Humans ; Longitudinal Studies ; Male ; Middle Aged ; Netherlands/epidemiology ; Neuroticism ; Patient Acceptance of Health Care/statistics & numerical data ; Personality Disorders/psychology ; Personality Inventory ; Physical Examination ; Prevalence ; Somatoform Disorders/psychology ; Surveys and Questionnaires ; Young Adult
    • نبذة مختصرة :
      Background: Medically unexplained physical symptoms (MUPS) are highly prevalent and are associated with frequent health care use (HCU). MUPS frequently co-occur with psychiatric disorders. With this study we examined the longitudinal association between MUPS and HCU over 2 years and the influence of depressive and anxiety disorders and personality traits on this association.
      Methods: We analysed follow-up data from 2045 to 2981 participants from the Netherlands Study of Depression and Anxiety (NESDA), a multisite cohort study. The study population included participants with a current depressive and/or anxiety disorder, participants with a lifetime risk and/or subthreshold symptoms for depressive and/or anxiety disorders and healthy controls. HCU, measured with the Trimbos and iMTA questionnaire on Costs associated with Psychiatric illness (TIC-P), was operationalized as the number of used medical services and the number of associated contacts. MUPS were measured with the Four Dimensional Symptoms Questionnaire, depressive and anxiety disorders with the Composite International Diagnostic Interview and personality traits with the NEO Five-Factory Inventory. Measurements were taken at baseline, 1 and 2 years follow-up. We used generalized estimating equations (GEE), using HCU at all three measurements as (multivariate) outcome. GEE also takes into account the dependency of observations within participants.
      Results: MUPS were positively associated with HCU over 2 years (medical services: RR 1.020, 95 % CI 1.017-1.022; contacts: RR 1.037, 95 % CI 1.030-1.044). Neuroticism and depression had the strongest influence on the associations. After adjustment for these factors, the associations between MUPS and HCU weakened, but remained significant (services: RR 1.011, 95 % CI 1.008-1.014; contacts: RR 1.023, 95 % CI 1.015-1.032).
      Conclusions: Our results show that MUPS were positively associated with HCU over 2 years, even after adjusting for depressive and anxiety disorders and personality traits.
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    • Contributed Indexing:
      Keywords: Anxiety disorders; Depressive disorders; Health care use; Medically unexplained physical symptoms; Personality traits; Somatisation
    • الموضوع:
      Date Created: 20160430 Date Completed: 20170724 Latest Revision: 20220330
    • الموضوع:
      20250114
    • الرقم المعرف:
      PMC4848781
    • الرقم المعرف:
      10.1186/s12913-016-1332-7
    • الرقم المعرف:
      27125311