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[KIM-1 and NGAL as potential biomarkers for the diagnosis and cancer progression].

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  • المؤلفون: Marchewka Z;Marchewka Z; Tacik A; Tacik A; Piwowar A; Piwowar A
  • المصدر:
    Postepy higieny i medycyny doswiadczalnej (Online) [Postepy Hig Med Dosw (Online)] 2016 Apr 18; Vol. 70, pp. 329-36. Date of Electronic Publication: 2016 Apr 18.
  • نوع النشر :
    Journal Article; Review
  • اللغة:
    Polish
  • معلومة اضافية
    • Transliterated Title:
      KIM-1 i NGAL jako potencjalne biomarkery w diagnostyce i rozwoju procesu nowotworowego.
    • المصدر:
      Publisher: Medical Science International Country of Publication: Poland NLM ID: 101206517 Publication Model: Electronic Cited Medium: Internet ISSN: 1732-2693 (Electronic) Linking ISSN: 00325449 NLM ISO Abbreviation: Postepy Hig Med Dosw (Online) Subsets: MEDLINE
    • بيانات النشر:
      Original Publication: [Warsaw, Poland] : Medical Science International, [2004]-
    • الموضوع:
      Acute-Phase Proteins/*urine ; Lipocalins/*urine ; Membrane Glycoproteins/*urine ; Neoplasms/*diagnosis ; Proto-Oncogene Proteins/*urine; Acute-Phase Proteins/metabolism ; Biomarkers/urine ; Disease Progression ; Hepatitis A Virus Cellular Receptor 1 ; Humans ; Lipocalin-2 ; Lipocalins/metabolism ; Membrane Glycoproteins/metabolism ; Neoplasms/urine ; Proto-Oncogene Proteins/metabolism ; Receptors, Virus/metabolism ; Urine Specimen Collection
    • نبذة مختصرة :
      On the basis of scientific literature, there is growing evidence that KIM-1 and NGAL are interesting and promising biomarkers not only in acute and chronic inflammatory processes but also in oncogenesis. There are a number of studies which investigate their possible use in diagnosis, treatment and monitoring of therapy effectiveness. The results of recent research suggests that they may play an important role in standard oncology practice. Simultaneous measurement of KIM-1 and NGAL in urine can play a crucial role in carcinogenesis assessment and cancer progression. In the future, they can become rapid diagnostic indicators, which allow one to determine cancer subtype leading to biopsy replacement and therapy improvement. In the present work, beside biochemical characteristics of KIM-1 and NGAL, we will also discuss their role in the diagnosis and assessment of development of cancer.
    • الرقم المعرف:
      0 (Acute-Phase Proteins)
      0 (Biomarkers)
      0 (HAVCR1 protein, human)
      0 (Hepatitis A Virus Cellular Receptor 1)
      0 (LCN2 protein, human)
      0 (Lipocalin-2)
      0 (Lipocalins)
      0 (Membrane Glycoproteins)
      0 (Proto-Oncogene Proteins)
      0 (Receptors, Virus)
    • الموضوع:
      Date Created: 20160428 Date Completed: 20160617 Latest Revision: 20220330
    • الموضوع:
      20250114
    • الرقم المعرف:
      10.5604/17322693.1199716
    • الرقم المعرف:
      27117109