Cutaneous histiocytoid Sweet syndrome and its relationship to hematological diseases.

Publisher: Wiley Country of Publication: United States NLM ID: 0425124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0560 (Electronic) Linking ISSN: 03036987 NLM ISO Abbreviation: J Cutan Pathol Subsets: MEDLINE

Publication: Malden, MA : Wiley
Original Publication: Copenhagen, Blackwell Munksgaard.

Anemia, Macrocytic*/complications ; Anemia, Macrocytic*/pathology ; Myelodysplastic Syndromes*/complications ; Myelodysplastic Syndromes*/pathology ; Sweet Syndrome*/etiology ; Sweet Syndrome*/pathology; Leukemia, Myeloid/*pathology ; Skin Neoplasms/*pathology; Aged, 80 and over ; Humans ; Male ; Middle Aged

Sweet syndrome (SS) was described over 50 years ago as a distinctive form of neutrophilic dermatosis. It may be idiopathic, drug-induced or paraneoplastic, and in the last of those subtypes, myeloproliferative diseases are prominently represented. A peculiar variant of SS is termed 'histiocytoid' SS (HSS), and early accounts of that condition asserted that it showed no linkage to hematological disorders. We herein report two additional cases of HSS--both of which were associated with myeloid dyscrasias--together with a review of the pertinent literature. Along with our observations, the latter process appears to contradict the contention that HSS has no relationship to hematopoietic diseases; between 35 and 55% of reported cases have indeed shown such an association, usually with myelogenous leukemia or myelodysplastic syndromes.
(© 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)

Keywords: Sweet syndrome; aseptic neutrophilic dermatosis; hematological dyscrasias paraneoplastic cutaneous diseases

Date Created: 20151224 Date Completed: 20161223 Latest Revision: 20161230

20240829

10.1111/cup.12659

26694973