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Infection control knowledge, beliefs and behaviours amongst cystic fibrosis patients with epidemic Pseudomonas aeruginosa.

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اقرأ أكثر حفظ في قائمتي
  • معلومة اضافية
    • المصدر:
      Publisher: BioMed Central Country of Publication: England NLM ID: 100968563 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2466 (Electronic) Linking ISSN: 14712466 NLM ISO Abbreviation: BMC Pulm Med Subsets: MEDLINE
    • بيانات النشر:
      Original Publication: London : BioMed Central, [2001]-
    • الموضوع:
      Health Knowledge, Attitudes, Practice* ; Infection Control* ; Pseudomonas aeruginosa*; Cystic Fibrosis/*psychology ; Pseudomonas Infections/*psychology; Adult ; Coinfection/epidemiology ; Cystic Fibrosis/epidemiology ; Epidemics ; Female ; Humans ; Male ; Mycobacterium Infections, Nontuberculous/epidemiology ; Nontuberculous Mycobacteria ; Peer Group ; Pseudomonas Infections/epidemiology ; Pseudomonas Infections/microbiology ; Retrospective Studies ; Risk Factors ; Social Support ; Staphylococcal Infections/epidemiology ; Staphylococcus aureus ; Young Adult
    • نبذة مختصرة :
      Background: Epidemic P. aeruginosa (ePA) infections are common in cystic fibrosis (CF) and have been associated with accelerated clinical decline. Factors associated with ePA are unclear, and evidence based infection control interventions are lacking.
      Methods: We prospectively collect all bacterial pathogens from adult CF patients. We performed PA strain typing on retrospectively collected enrollment samples and recent isolates to identify patients infected with ePA. All patients attending our clinic were approached to complete a survey on infection control knowledge, beliefs and exposures. We analyzed responses of those with ePA relative to the entire cohort without ePA as well as those infected with unique strains of P. aeruginosa to assess for risk factors for ePA and differences in infection control knowledge, beliefs or behaviours.
      Results: Of 144 participants, 30 patients had ePA (two Liverpool epidemic strain, 28 Prairie epidemic strain), 83 % of which had established infection prior to transition to the adult clinic. Risk of concomitant infecting pathogens was no different between groups although, Staphylococcus aureus and non-tuberculous mycobacteria were less common in those with ePA. Patients with ePA were more likely to have attended CF-camp and have a history of CF fundraising. Patients with ePA did not differ with respect to beliefs regarding pathogens or transmission risk, except they believed indirect contact posed little risk. Furthermore, patients with ePA were more likely to continue to associate with others with CF despite extensive counselling. Use of peer-peer online networking was minimal in both groups.
      Conclusion: Infections with ePA are closely linked to past exposures, now routinely discouraged. As socialization is the greatest risk factor for ePA, infection control strategies for ePA must focus on discouraging face-to-face interactions amongst CF patients. As peer support remains a desire amongst patients, investment in technologies and strategies that enable indirect communication and support are required.
    • References:
      GMS Hyg Infect Control. 2014 Sep 30;9(3):Doc20. (PMID: 25285264)
      Infect Control Hosp Epidemiol. 2014 Aug;35 Suppl 1:S1-S67. (PMID: 25025126)
      Lancet. 1996 Sep 7;348(9028):639-42. (PMID: 8782753)
      J Hosp Infect. 1983 Mar;4(1):31-40. (PMID: 6190882)
      Thorax. 2009 Nov;64(11):926-31. (PMID: 19574243)
      J Cyst Fibros. 2012 May;11(3):173-9. (PMID: 22146482)
      Am J Respir Crit Care Med. 2005 Feb 1;171(3):257-60. (PMID: 15542795)
      Health Expect. 2016 Apr;19(2):309-21. (PMID: 25691209)
      J Clin Microbiol. 2016 Feb;54(2):489-91. (PMID: 26659208)
      Eur Respir J. 2012 Jul;40(1):227-38. (PMID: 22323572)
      Am J Infect Control. 2013 Feb;41(2):100-6. (PMID: 23369314)
      Expert Rev Respir Med. 2010 Aug;4(4):519-29. (PMID: 20658913)
      Thorax. 1997 Apr;52(4):318-21. (PMID: 9196512)
      Lancet. 2001 Aug 18;358(9281):558-60. (PMID: 11520530)
      Am J Respir Crit Care Med. 2002 Oct 1;166(7):983-7. (PMID: 12359658)
      J Clin Microbiol. 1991 Jun;29(6):1265-7. (PMID: 1907611)
      Pediatr Pulmonol. 2000 Mar;29(3):177-81. (PMID: 10686037)
      J Med Microbiol. 2004 Jul;53(Pt 7):609-15. (PMID: 15184530)
      Curr Opin Pulm Med. 2009 Nov;15(6):626-31. (PMID: 19644375)
      J Pediatr. 2002 Oct;141(4):512-7. (PMID: 12378190)
      Pediatr Pulmonol. 2008 Sep;43(9):900-7. (PMID: 18671274)
      Chest. 2010 Jun;137(6):1405-9. (PMID: 20081099)
      JAMA. 2010 Nov 17;304(19):2145-53. (PMID: 21081727)
      Eur Respir J. 2004 Jul;24(1):101-6. (PMID: 15293611)
      Am J Respir Crit Care Med. 2005 May 1;171(9):1020-5. (PMID: 15709051)
      Pediatr Pulmonol. 2012 Feb;47(2):144-52. (PMID: 22241572)
      J Clin Microbiol. 2014 Apr;52(4):1127-35. (PMID: 24452167)
      Pediatr Pulmonol. 2011 Mar;46(3):295-301. (PMID: 20967838)
      J Med Microbiol. 2013 Jul;62(Pt 7):988-1000. (PMID: 23558134)
      J Cyst Fibros. 2003 Mar;2(1):29-34. (PMID: 15463843)
      J Clin Microbiol. 2010 Jul;48(7):2592-4. (PMID: 20463160)
      JRSM Short Rep. 2013 Jan;4(1):1. (PMID: 23413403)
      Respir Care. 2003 Jan;48(1):24-8. (PMID: 12556258)
      Thorax. 2004 Apr;59(4):334-6. (PMID: 15047956)
      Am J Respir Crit Care Med. 2015 Mar 1;191(5):598-601. (PMID: 25723827)
    • الموضوع:
      Date Created: 20151107 Date Completed: 20160628 Latest Revision: 20181113
    • الموضوع:
      20231215
    • الرقم المعرف:
      PMC4635525
    • الرقم المعرف:
      10.1186/s12890-015-0116-x
    • الرقم المعرف:
      26542115