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The experimental teaching reform in biochemistry and molecular biology for undergraduate students in Peking University Health Science Center.

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  • المؤلفون: Yang X;Yang X; Sun L; Sun L; Zhao Y; Zhao Y; Yi X; Yi X; Zhu B; Zhu B; Wang P; Wang P; Lin H; Lin H; Ni J; Ni J
  • المصدر:
    Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology [Biochem Mol Biol Educ] 2015 Nov-Dec; Vol. 43 (6), pp. 428-33. Date of Electronic Publication: 2015 Oct 07.
  • نوع النشر :
    Journal Article; Research Support, Non-U.S. Gov't
  • اللغة:
    English
  • معلومة اضافية
    • المصدر:
      Publisher: John Wiley & sons Country of Publication: United States NLM ID: 100970605 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1539-3429 (Electronic) Linking ISSN: 14708175 NLM ISO Abbreviation: Biochem Mol Biol Educ Subsets: MEDLINE
    • بيانات النشر:
      Publication: 2002- : Hoboken, NJ : John Wiley & sons
      Original Publication: Oxford, UK : Elsevier, c2000-
    • الموضوع:
      Biochemistry/*education ; Molecular Biology/*education; China ; Comprehension ; Curriculum ; Female ; Humans ; Laboratories ; Learning ; Male ; Research Design ; Students ; Universities ; Young Adult
    • نبذة مختصرة :
      Since 2010, second-year undergraduate students of an eight-year training program leading to a Doctor of Medicine degree or Doctor of Philosophy degree in Peking University Health Science Center (PKUHSC) have been required to enter the "Innovative talent training project." During that time, the students joined a research lab and participated in some original research work. There is a critical educational need to prepare these students for the increasing accessibility of research experience. The redesigned experimental curriculum of biochemistry and molecular biology was developed to fulfill such a requirement, which keeps two original biochemistry experiments (Gel filtration and Enzyme kinetics) and adds a new two-experiment component called "Analysis of anti-tumor drug induced apoptosis." The additional component, also known as the "project-oriented experiment" or the "comprehensive experiment," consists of Western blotting and a DNA laddering assay to assess the effects of etoposide (VP16) on the apoptosis signaling pathways. This reformed laboratory teaching system aims to enhance the participating students overall understanding of important biological research techniques and the instrumentation involved, and to foster a better understanding of the research process all within a classroom setting. Student feedback indicated that the updated curriculum helped them improve their operational and self-learning capability, and helped to increase their understanding of theoretical knowledge and actual research processes, which laid the groundwork for their future research work.
      (© 2015 The International Union of Biochemistry and Molecular Biology.)
    • Contributed Indexing:
      Keywords: DNA ladder assay; Western blotting; experimental teaching reform; project-oriented experiment
    • الموضوع:
      Date Created: 20151008 Date Completed: 20161027 Latest Revision: 20161230
    • الموضوع:
      20231215
    • الرقم المعرف:
      10.1002/bmb.20890
    • الرقم المعرف:
      26442905