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A Randomized Comparative Effectiveness Trial for Preventing Type 2 Diabetes.

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  • معلومة اضافية
    • المصدر:
      Publisher: American Public Health Association Country of Publication: United States NLM ID: 1254074 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1541-0048 (Electronic) Linking ISSN: 00900036 NLM ISO Abbreviation: Am J Public Health Subsets: MEDLINE
    • بيانات النشر:
      Publication: Washington, DC : American Public Health Association
      Original Publication: New York [etc.]
    • الموضوع:
      Poverty*; Counseling/*organization & administration ; Diabetes Mellitus, Type 2/*prevention & control ; Overweight/*therapy ; Weight Reduction Programs/*organization & administration; Adult ; Blood Glucose ; Body Mass Index ; Female ; Health Behavior ; Humans ; Indiana ; Life Style ; Male ; Middle Aged ; Obesity/therapy ; Single-Blind Method ; Weight Loss
    • نبذة مختصرة :
      Objectives: We evaluated the weight loss effectiveness of a YMCA model for the Diabetes Prevention Program (DPP) lifestyle intervention.
      Methods: Between July 2008 and November 2010, we individually randomized 509 overweight or obese, low-income, nondiabetic adults with elevated blood glucose in Indianapolis, Indiana, to receive standard care plus brief lifestyle counseling or be offered a group-based YMCA adaptation of the DPP (YDPP). Primary outcome was mean weight loss difference at 12 months. In our intention-to-treat analyses, we used longitudinal linear or logistic regression, multiply imputing missing observations. We used instrumental variables regression to estimate weight loss effectiveness among participants completing 9 or more intervention lessons.
      Results: In the YDPP arm, 161 (62.6%) participants attended ≥ 1 lesson and 103 (40.0%) completed 9 or more lessons. In intention-to-treat analysis, mean 12-month weight loss was 2.3 kilograms (95% confidence interval [CI] = 1.1, 3.4 kg) more for the YDPP arm than for standard care participants. In instrumental variable analyses, persons attending 9 or more lessons had a 5.3-kilogram (95% CI = 2.8, 7.9 kg) greater weight loss than did those with standard care alone.
      Conclusions: The YMCA model for DPP delivery achieves meaningful weight loss at 12 months among low-income adults.
    • References:
      N Engl J Med. 2002 Feb 7;346(6):393-403. (PMID: 11832527)
      Am J Health Syst Pharm. 2002 Sep 15;59(18):1774-9. (PMID: 12298117)
      Health Serv Res. 2002 Oct;37(5):1145-58. (PMID: 12479490)
      Diabetes Care. 2003 Jan;26(1):36-47. (PMID: 12502656)
      Diabetes Care. 2003 Sep;26(9):2670-4. (PMID: 12941736)
      Ann Intern Med. 2003 Dec 2;139(11):933-49. (PMID: 14644897)
      Obes Res. 2004 Sep;12(9):1426-34. (PMID: 15483207)
      Ann Clin Biochem. 1994 Jul;31 ( Pt 4):367-70. (PMID: 7979104)
      J Cardiopulm Rehabil. 1997 Nov-Dec;17(6):413-8. (PMID: 9421763)
      Pediatr Diabetes. 2005 Mar;6(1):13-6. (PMID: 15787896)
      Diabetes Care. 2005 Apr;28(4):888-94. (PMID: 15793191)
      Stat Med. 2006 Aug 30;25(16):2737-61. (PMID: 16287216)
      Diabetes Care. 2006 Sep;29(9):2102-7. (PMID: 16936160)
      Diabetes Educ. 2007 Jan-Feb;33(1):69, 74-5, 77-8. (PMID: 17272794)
      Diabetes Care. 2007 Jun;30(6):1374-83. (PMID: 17363746)
      Diabetes Educ. 2009 Mar-Apr;35(2):224-8, 232. (PMID: 19321808)
      JAMA. 2010 Jan 20;303(3):235-41. (PMID: 20071471)
      Contemp Clin Trials. 2010 Jan;31(1):71-81. (PMID: 19758580)
      BMJ. 2010;340:c2073. (PMID: 20442226)
      Contemp Clin Trials. 2011 Jan;32(1):40-9. (PMID: 20974289)
      Diabetes Care. 2011 Jul;34(7):1451-7. (PMID: 21593290)
      Chronic Illn. 2011 Dec;7(4):279-90. (PMID: 21840914)
      Health Technol Assess. 2011 Dec;15(44):i-xii, 1-254. (PMID: 22182828)
      Health Aff (Millwood). 2012 Jan;31(1):67-75. (PMID: 22232096)
      Curr Diab Rep. 2012 Apr;12(2):138-46. (PMID: 22350807)
      Diabet Med. 2013 Jan;30(1):46-55. (PMID: 22812594)
      N Engl J Med. 2013 Jul 11;369(2):145-54. (PMID: 23796131)
      Contemp Clin Trials. 2014 Jan;37(1):1-9. (PMID: 24177413)
      J Community Health. 2014 Dec;39(6):1179-85. (PMID: 24752958)
    • Grant Information:
      UL1RR025741 United States RR NCRR NIH HHS; UL1 RR025741 United States RR NCRR NIH HHS; UL1 TR001108 United States TR NCATS NIH HHS; UL1 TR001422 United States TR NCATS NIH HHS; R18 DK079855 United States DK NIDDK NIH HHS
    • الرقم المعرف:
      0 (Blood Glucose)
    • الموضوع:
      Date Created: 20150918 Date Completed: 20160126 Latest Revision: 20220330
    • الموضوع:
      20221213
    • الرقم المعرف:
      PMC4605179
    • الرقم المعرف:
      10.2105/AJPH.2015.302641
    • الرقم المعرف:
      26378828