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Evaluation of stability and capsular bag opacification of a new foldable adjustable intraocular lens.

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اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي
  • معلومة اضافية
    • المصدر:
      Publisher: Wiley-Blackwell Pub. Asia Country of Publication: Australia NLM ID: 100896531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1442-9071 (Electronic) Linking ISSN: 14426404 NLM ISO Abbreviation: Clin Exp Ophthalmol Subsets: MEDLINE
    • بيانات النشر:
      Publication: Carlton, Vic. : Wiley-Blackwell Pub. Asia
      Original Publication: Carlton, Vic. : Blackwell Science Asia, c2000-
    • الموضوع:
      Lens Implantation, Intraocular* ; Lenses, Intraocular* ; Phacoemulsification* ; Prosthesis Design*; Artificial Lens Implant Migration/*prevention & control ; Capsule Opacification/*prevention & control; Animals ; Anterior Eye Segment/pathology ; Materials Testing ; Rabbits ; Slit Lamp
    • نبذة مختصرة :
      Background: Incorrect lens power remains one of the most common reasons for intraocular lens explantation/exchange. We evaluated stability and effect on capsular bag opacification of a new foldable modular lens system, with a base component and an optic component in rabbit eyes.
      Methods: Bilateral phacoemulsification was performed on six rabbits; one eye received the test lens (Harmoni Modular Lens, ClarVista Medical), whereas the other received a single-piece hydrophobic acrylic control lens (SA60AT, Alcon). Slit-lamp examinations were performed at postoperative weeks 1, 2, 3, 4 and 6. All rabbits were sacrificed at week 6. After enucleation, the eyes were examined grossly from the Miyake-Apple view. Following, all globes were sectioned and processed for histopathological examination.
      Results: The modular lens was stable in all six rabbits. Uveal biocompatibility was similar to or better in the test eyes when compared with control eyes up to 6 weeks postoperatively. Overall, capsular bag opacification was found to be significantly lower in the test eyes when compared with control eyes. At the 6-week gross examination, central posterior capsule opacification was scored as 0.58 ± 0.73 in the test group, and as 3.00 ± 1.26 in the control group (paired two samples for means t-test; two-tail P = 0.005).
      Conclusions: The Harmoni Modular system remains stable within the capsular bag after implantation. Due to the design of the base component featuring long loops, along with peripheral anterior and posterior square edges, the lens appeared to prevent overall capsular bag opacification in the rabbit model.
      (© 2015 Royal Australian and New Zealand College of Ophthalmologists.)
    • Contributed Indexing:
      Keywords: cataract surgery; intraocular lens; posterior capsule opacification
    • الموضوع:
      Date Created: 20150325 Date Completed: 20160411 Latest Revision: 20160831
    • الموضوع:
      20250114
    • الرقم المعرف:
      10.1111/ceo.12526
    • الرقم المعرف:
      25801178