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Neighborhood disadvantage, preconception stressful life events, and infant birth weight.

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  • المؤلفون: Witt WP;Witt WP; Park H; Wisk LE; Cheng ER; Mandell K; Chatterjee D; Zarak D
  • المصدر:
    American journal of public health [Am J Public Health] 2015 May; Vol. 105 (5), pp. 1044-52. Date of Electronic Publication: 2015 Mar 19.
  • نوع النشر :
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • اللغة:
    English
  • معلومة اضافية
    • المصدر:
      Publisher: American Public Health Association Country of Publication: United States NLM ID: 1254074 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1541-0048 (Electronic) Linking ISSN: 00900036 NLM ISO Abbreviation: Am J Public Health Subsets: MEDLINE
    • بيانات النشر:
      Publication: Washington, DC : American Public Health Association
      Original Publication: New York [etc.]
    • الموضوع:
      Infant, Very Low Birth Weight* ; Life Change Events* ; Poverty*; Residence Characteristics/*statistics & numerical data ; Stress, Psychological/*epidemiology; Chronic Disease ; Health Behavior ; Humans ; Longitudinal Studies ; Socioeconomic Factors
    • نبذة مختصرة :
      Objectives: We sought to determine whether the effects of preconception stressful life events (PSLEs) on birth weight differed by neighborhood disadvantage.
      Methods: We drew our data from the Early Childhood Longitudinal Study, Birth Cohort (2001-2002; n = 9300). We created a neighborhood disadvantage index (NDI) using county-level data from the 2000 US Census. We grouped the NDI into tertiles that represented advantaged, middle advantaged, and disadvantaged neighborhoods. Stratified multinomial logistic regressions estimated the effect of PSLEs on birth weight, controlling for confounders.
      Results: We found a gradient in the relationship between women's exposure to PSLEs and having a very low birth weight (VLBW) infant by NDI tertile; the association was strongest in disadvantaged neighborhoods (adjusted odd ratio [AOR] = 1.62; 95% confidence interval [CI] = 1.04, 2.53), followed by middle (AOR = 1.39; 95% CI = 1.00, 1.93) and advantaged (AOR = 1.29; 95% CI = 0.91, 1.82) neighborhoods. We observed a similar gradient for women with chronic conditions and among minority mothers.
      Conclusions: Women who experienced PSLEs, who had chronic conditions, or were racial/ethnic minorities had the greatest risk of having VLBW infants if they lived in disadvantaged neighborhoods; this suggests exacerbation of risk within disadvantaged environments. Interventions to reduce rates of VLBW should focus on reducing the deleterious effects of stressors and on improving neighborhood conditions.
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    • Grant Information:
      T32 HD075727 United States HD NICHD NIH HHS; T32HP22239 United States PHS HHS; T32 HS00083 United States HS AHRQ HHS; T32 HS000083 United States HS AHRQ HHS; T32 HS000063 United States HS AHRQ HHS; T32-HD075727 United States HD NICHD NIH HHS; 2T32HS000063-20 United States HS AHRQ HHS; R40MC23625 United States PHS HHS
    • Contributed Indexing:
      Indexing Agency: NLM Local ID #: HHSPA752953.
    • الموضوع:
      Date Created: 20150320 Date Completed: 20150615 Latest Revision: 20181113
    • الموضوع:
      20221213
    • الرقم المعرف:
      PMC4386492
    • الرقم المعرف:
      10.2105/AJPH.2015.302566
    • الرقم المعرف:
      25790423