Higher cortisol awakening response in young adolescents with persistent anxiety problems.

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المؤلفون: Greaves‐Lord, K.¹ (AUTHOR); Ferdinand, R. F.^1,2 (AUTHOR); Oldehinkel, A. J.^1,2,3 (AUTHOR); Sondeijker, F. E. P. L.¹ (AUTHOR); Ormel, J.^2,3 (AUTHOR); Verhulst, F. C.¹ (AUTHOR)
المصدر:
Acta Psychiatrica Scandinavica. Aug2007, Vol. 116 Issue 2, p137-144. 8p. 1 Graph.
الموضوع:
*ANXIETY disorders; *YOUNG adult psychology; *HYPOTHALAMIC-pituitary-adrenal axis; *HYDROCORTISONE; *HYPOTHALAMUS; *PARENT-child relationships

معلومة اضافية
- نبذة مختصرة :
  Objective: The aims of the present study were to test the association between current anxiety problems and basal cortisol levels in a large population sample of young preadolescents, and to test if HPA-axis activity differs between individuals with no, only current, or persistent anxiety problems. Method: Cortisol levels of 10- to 12-year olds ( n = 1768) from the general population were measured on three time points during the day. A self-report questionnaire (RCADS) was used to assess current anxiety, a parent-report questionnaire (TPBQ) to assess anxiety problems at age 4. Results: Associations between cortisol levels and current anxiety problems were not found. However, individuals with persistent anxiety problems had higher morning cortisol levels and a higher cortisol awakening response. Conclusion: Apparently, only persistent, and not current, anxiety problems are associated with higher HPA-axis activity. Alterations in HPA-axis activity might underlie persistent anxiety problems, or result from the stress accompanied by persistent anxiety problems. [ABSTRACT FROM AUTHOR]