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Assessment of selenium and mercury in biological samples of normal and night blindness children of age groups (3-7) and (8-12) years.

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  • معلومة اضافية
    • المصدر:
      Publisher: Springer Country of Publication: Netherlands NLM ID: 8508350 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2959 (Electronic) Linking ISSN: 01676369 NLM ISO Abbreviation: Environ Monit Assess Subsets: MEDLINE
    • بيانات النشر:
      Publication: 1998- : Dordrecht : Springer
      Original Publication: Dordrecht, Holland ; Boston : D. Reidel Pub. Co., c1981-
    • الموضوع:
      Environmental Exposure/*statistics & numerical data ; Environmental Pollutants/*metabolism ; Mercury/*metabolism ; Night Blindness/*metabolism ; Selenium/*metabolism; Acids ; Child ; Child, Preschool ; Environmental Exposure/analysis ; Environmental Monitoring ; Female ; Hair/chemistry ; Humans ; Male ; Mercury/analysis ; Selenium/analysis ; Spectrophotometry, Atomic
    • نبذة مختصرة :
      The causes of night blindness in children are multifactorial and particular consideration has been given to childhood nutritional deficiency, which is the most common problem found in underdeveloped countries. Such deficiency can result in physiological and pathological processes that in turn influence biological sample composition. This study was designed to compare the levels of selenium (Se) and mercury (Hg) in scalp hair, blood, and urine of night blindness children age ranged (3-7) and (8-12) years of both genders, comparing them to sex- and age-matched controls. A microwave-assisted wet acid digestion procedure was developed as a sample pretreatment for the determination of Se and Hg in biological samples of night blindness children. The proposed method was validated by using conventional wet digestion and certified reference samples of hair, blood, and urine. The Se and Hg in biological samples were measured by electrothermal atomic absorption spectrometry and cold vapor atomic absorption spectrometry, prior to microwave acid digestion, respectively. The concentration of Se was decreased in scalp hair and blood samples of male and female night blindness children while Hg was higher in all biological samples as compared to referent subjects. The Se concentration was inversely associated with the risk of night blindness in both genders. These results add to an increasing body of evidence that Se is a protecting element for night blindness. These data present guidance to clinicians and other professional investigating deficiency of essential micronutrients in biological samples (scalp hair and blood) of night blindness children.
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    • الرقم المعرف:
      0 (Acids)
      0 (Environmental Pollutants)
      FXS1BY2PGL (Mercury)
      H6241UJ22B (Selenium)
    • الموضوع:
      Date Created: 20150207 Date Completed: 20150709 Latest Revision: 20181202
    • الموضوع:
      20240829
    • الرقم المعرف:
      10.1007/s10661-014-4201-z
    • الرقم المعرف:
      25655123