Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request

Mild cognitive impairment and depressive symptoms in elderly patients with diabetes: prevalence, risk factors, and comorbidity.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
  • معلومة اضافية
    • المصدر:
      Publisher: Hindawi Limited Country of Publication: England NLM ID: 101605237 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2314-6753 (Electronic) NLM ISO Abbreviation: J Diabetes Res Subsets: MEDLINE
    • بيانات النشر:
      Publication: <2019>-: London, United Kingdom : Hindawi Limited
      Original Publication: Nasr City, Cairo : Hindawi Publishing Corporation, [2013]-
    • الموضوع:
    • نبذة مختصرة :
      The aim of the study was to estimate the prevalence of mild cognitive impairment (MCI), depressive syndrome cases, and its comorbidity, and to identify predictors of these conditions. Methods. 276 diabetics elders were screened for MCI and depressive symptoms. Detailed information of history of diabetes, and data of BMI, HbA1c, and blood lipids were collected. Results. The prevalence of MCI was 31.5%, depressive syndrome was 29.7%, and MCI with coexisting depressive mood was 9.1%. The logistic regression analysis revealed that variables which increased the likelihood of having been diagnosed with MCI were: higher HbA1c level, previous CVD, hypertension, retinopathy, increased number of comorbidities, and less years of formal education. Significant predictors of having a depressive mood included female gender, single marital status, current and past smoking status, lack of physical activity, higher BMI and total cholesterol level, increased number of comorbidities, history of hypoglycemia, and insulin treatment. Factors associated with both MCI and depressive syndrome were female gender, single marital status, past smoking status, retinopathy, previous CVD or stroke, increased number of comorbidities, and insulin treatment. Conclusions. Depressive symptoms, MCI, and its comorbidity are common in elderly subjects with type 2 diabetes. Systematic screening could result in the identification of high-risk patients.
    • References:
      Geriatr Gerontol Int. 2012 Apr;12 Suppl 1:103-9. (PMID: 22435945)
      Psychosom Med. 2005 Jan-Feb;67(1):46-51. (PMID: 15673623)
      Nat Rev Neurosci. 2004 May;5(5):347-60. (PMID: 15100718)
      Arch Neurol. 2007 Apr;64(4):570-5. (PMID: 17420320)
      Int J Geriatr Psychiatry. 2012 Mar;27(3):271-9. (PMID: 21448864)
      Diabetologia. 2010 Dec;53(12):2480-6. (PMID: 20711716)
      Diabetes Metab Res Rev. 2010 Oct;26(7):507-19. (PMID: 20799243)
      Eur Heart J. 2008 May;29(9):1110-7. (PMID: 18400765)
      Intern Med J. 2012 May;42(5):484-91. (PMID: 22372522)
      Am J Epidemiol. 2001 Oct 1;154(7):635-41. (PMID: 11581097)
      Dement Geriatr Cogn Dis Extra. 2011 Jan;1(1):1-9. (PMID: 22163228)
      J Am Geriatr Soc. 2005 Apr;53(4):695-9. (PMID: 15817019)
      Biomed Res Int. 2013;2013:186106. (PMID: 23936778)
      Diabetes. 2010 Nov;59(11):2883-9. (PMID: 20798334)
      Diabetes Care. 2011 Dec;34(12):2586-90. (PMID: 22011410)
      Endocr Rev. 2008 Jun;29(4):494-511. (PMID: 18436709)
      N Engl J Med. 2007 May 3;356(18):1842-52. (PMID: 17476010)
      J Intern Med. 2004 Sep;256(3):183-94. (PMID: 15324362)
      Am J Geriatr Psychiatry. 2010 Feb;18(2):98-116. (PMID: 20104067)
      J Gen Intern Med. 2008 Oct;23(10):1634-41. (PMID: 18668297)
      Gerontologist. 1969 Autumn;9(3):179-86. (PMID: 5349366)
      J Neurol Neurosurg Psychiatry. 2006 Jun;77(6):714-8. (PMID: 16549412)
      Gerontologist. 1970 Spring;10(1):20-30. (PMID: 5420677)
      Arch Gen Psychiatry. 2006 Mar;63(3):273-9. (PMID: 16520432)
      BMC Public Health. 2014;14:163. (PMID: 24524353)
      Cell Metab. 2008 Jun;7(6):476-84. (PMID: 18522829)
      Diabetes Care. 2009 Feb;32(2):221-6. (PMID: 19171735)
      J Psychiatr Res. 1982-1983;17(1):37-49. (PMID: 7183759)
      Lancet. 2005 Apr 9-15;365(9467):1333-46. (PMID: 15823385)
    • الرقم المعرف:
      0 (Biomarkers)
      0 (Glycated Hemoglobin A)
      0 (Lipids)
      0 (hemoglobin A1c protein, human)
    • الموضوع:
      Date Created: 20141129 Date Completed: 20150707 Latest Revision: 20221207
    • الموضوع:
      20231215
    • الرقم المعرف:
      PMC4241577
    • الرقم المعرف:
      10.1155/2014/179648
    • الرقم المعرف:
      25431771