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The Manchester Uveitis Clinic: The first 3000 patients, 2: Uveitis Manifestations, Complications, Medical and Surgical Management.

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  • المؤلفون: Jones NP;Jones NP
  • المصدر:
    Ocular immunology and inflammation [Ocul Immunol Inflamm] 2015 Apr; Vol. 23 (2), pp. 127-34. Date of Electronic Publication: 2014 Nov 13.
  • نوع النشر :
    Journal Article; Multicenter Study
  • اللغة:
    English
  • معلومة اضافية
    • المصدر:
      Publisher: Informa Healthcare Country of Publication: England NLM ID: 9312169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-5078 (Electronic) Linking ISSN: 09273948 NLM ISO Abbreviation: Ocul Immunol Inflamm Subsets: MEDLINE
    • بيانات النشر:
      Publication: London : Informa Healthcare
      Original Publication: Buren, The Netherlands : Aeolus Press, c1993-
    • الموضوع:
      Glaucoma/*etiology ; Immunosuppression Therapy/*methods ; Macular Edema/*etiology ; Ophthalmologic Surgical Procedures/*methods ; Uveitis/*epidemiology; Adult ; Aged ; Female ; Follow-Up Studies ; Glaucoma/epidemiology ; Humans ; Incidence ; Macular Edema/epidemiology ; Male ; Middle Aged ; Prognosis ; Retrospective Studies ; United Kingdom/epidemiology ; Uveitis/complications ; Uveitis/therapy ; Visual Acuity
    • نبذة مختصرة :
      Purpose: To demonstrate the manifestations and complications of uveitis, and their medical and surgical management, in a very large group of patients attending the Manchester Uveitis Clinic (MUC), a specialist uveitis clinic in the Northwest of England, UK.
      Methods: Retrospective retrieval of data on a computerized database incorporating all new referrals to MUC from 1991 to 2013.
      Results: A total of 3000 new patients with uveitis were seen during a 22-year period, of which 25.2% had a single acute episode, 13.6% had acute recurrent uveitis, 20.2% had chronic fluctuating uveitis, and 41.0% had chronic unremitting uveitis. The commonest complications were cataract (35% of patients), macular edema (20.5%), and glaucoma (19.5%). Oral steroids were required in 36% of patients, oral immunosuppression in 16%, and biologic treatment in 2%. Major intraocular surgery was required in 28%.
      Conclusions: Oral steroid usage is not an independent risk factor for cataract formation in patients with uveitis. Oral immunosuppression usage has increased 4-fold during this study period.
    • Contributed Indexing:
      Keywords: Cataract; complications; glaucoma; immunosuppression; macular edema; uveitis
    • الموضوع:
      Date Created: 20141114 Date Completed: 20160126 Latest Revision: 20220408
    • الموضوع:
      20240829
    • الرقم المعرف:
      10.3109/09273948.2014.968671
    • الرقم المعرف:
      25393634