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Geographic distribution of non-clinical Theileria parva infection among indigenous cattle populations in contrasting agro-ecological zones of Uganda: implications for control strategies.

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  • المؤلفون: Kabi F;Kabi F; Masembe C; Muwanika V; Kirunda H; Negrini R
  • المصدر:
    Parasites & vectors [Parasit Vectors] 2014 Sep 01; Vol. 7, pp. 414. Date of Electronic Publication: 2014 Sep 01.
  • نوع النشر :
    Journal Article; Research Support, Non-U.S. Gov't
  • اللغة:
    English
  • معلومة اضافية
    • المصدر:
      Publisher: BioMed Central Country of Publication: England NLM ID: 101462774 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-3305 (Electronic) Linking ISSN: 17563305 NLM ISO Abbreviation: Parasit Vectors Subsets: MEDLINE
    • بيانات النشر:
      Original Publication: London : BioMed Central
    • الموضوع:
      Agriculture* ; Ecosystem* ; Theileria parva*; Theileriasis/*parasitology; Animals ; Cattle ; Female ; Male ; Prevalence ; Theileriasis/epidemiology ; Uganda/epidemiology
    • نبذة مختصرة :
      Background: Non-clinical Theileria parva infection among indigenous cattle occurs upon recovery from primary disease during the first year of life. Continuous exposure to infection through contaminated tick infestations with absence of clinical disease gives rise to endemic stability. Endemic stable populations may become sources of infection if contaminated tick vectors are shared with susceptible exotic cattle. This study aimed at establishing a nationwide distribution of non-clinical T. parva infection among indigenous cattle populations to inform novel control strategies.
      Methods: The occurrence of non-clinical T. parva infection among apparently healthy 925 indigenous cattle from 209 herds spread out in 10 agro-ecological zones (AEZs) was determined using a nested PCR assay. The influence of AEZ, breed, sex, age and farmers' ranking of ECF importance were interrogated for influence of non-clinical parasite occurrence.
      Results: The overall prevalence of non-clinical T. parva infection was 30% (278/925). A gradual increase of non-clinical T. parva infection was observed ranging from 17% (95% CI: 0.03-0.23) to 43% (95% CI: 0.3-0.55) in the North Eastern Savannah Grasslands (NESG) to the Western Highland Ranges (WHR) respectively. A similarly associated 18% (95% CI: 0.07-0.28) and 35% (95% CI: 0.3-0.39) non-clinical parasite prevalence was observed among the East African shorthorn Zebu (EASZ) and Ankole cattle respectively. Average herd level non-clinical T. parva prevalence was 28%, ranging from zero to 100%. The likelihood of non-clinical T. parva infection was 35.5% greater in the western highlands compared to the northeastern semi-arid AEZs.
      Conclusions: Non-clinical T. parva occurs countrywide, structured along patterns of AEZ and breed gradients. These findings may guide policy formulation, deployment of integrated control strategies and local cattle improvement programs.
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    • الموضوع:
      Date Created: 20140902 Date Completed: 20150518 Latest Revision: 20211021
    • الموضوع:
      20231215
    • الرقم المعرف:
      PMC4261563
    • الرقم المعرف:
      10.1186/1756-3305-7-414
    • الرقم المعرف:
      25175844