Measurement of the difference in intraocular pressure between the sitting and lying body positions in healthy subjects: direct comparison of the Icare Pro with the Goldmann applanation tonometer, Pneumatonometer and Tonopen XL.

Publisher: Wiley-Blackwell Pub. Asia Country of Publication: Australia NLM ID: 100896531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1442-9071 (Electronic) Linking ISSN: 14426404 NLM ISO Abbreviation: Clin Exp Ophthalmol Subsets: MEDLINE

Publication: Carlton, Vic. : Wiley-Blackwell Pub. Asia
Original Publication: Carlton, Vic. : Blackwell Science Asia, c2000-

Intraocular Pressure/*physiology ; Posture/*physiology ; Tonometry, Ocular/*instrumentation; Adult ; Female ; Healthy Volunteers ; Humans ; Male ; Middle Aged ; Pilot Projects ; Prospective Studies ; Reproducibility of Results ; Young Adult

Background: Change in intraocular pressure is known to occur with body posture. Previously, markedly different estimations of this change were reported. The Icare Pro (Icare; Tiolat Oy, Helsinki, Finland) is designed to measure intraocular pressure with the subject supine. We compared the measurement of postural change in intraocular pressure obtained with this and 3 other tonometers: Goldmann applanation tonometer (CSO, Firenze, Italy), Pneumatonometer (Model 30, Reichert, Depew, NY, USA) and the Tonopen XL (Reichert).
Design: Prospective comparative study.
Participants: Twenty-one healthy subjects.
Methods: Intraocular pressure was measured in random order with four tonometers, first sitting then after 10 min of lying.
Main Outcome Measures: Average postural intraocular pressure change (mmHg) and the 95% limits of agreement for measuring postural intraocular pressure change between tonometers.
Results: Average postural intraocular pressure change (lying minus sitting, mmHg) was measured highest with the Goldmann applanation tonometer (4.1 ± 2.6) and Pneumatonometer (3.9 ± 2.1), significantly lower with the Tonopen (0.9 ± 1.7) and was negative with the Icare (-0.9 ± 3.3). The 95% limits of agreement for measuring postural intraocular pressure change between Goldmann applanation tonometer and Icare, Pneumatonometer and Tonopen were -3.2-13.3, -6.4-6.9 and -2.8-9.4 mmHg, respectively.
Conclusions: Postural change in intraocular pressure was measured similarly, on average, with Goldmann applanation tonometer and Pneumatonometer, and much lower with Tonopen and Icare Pro. There was poor interdevice agreement in measuring this parameter. We observed high intersubject variability, suggesting the clinical importance of this measurement in the diagnosis and management of glaucoma.
(© 2013 Royal Australian and New Zealand College of Ophthalmologists.)

Keywords: Goldmann; Icare Pro; Pneumatonometer; supine

Date Created: 20131205 Date Completed: 20150330 Latest Revision: 20160831

20230127

10.1111/ceo.12272

24299102