A study on ovine pneumonic pasteurellosis: isolation and identification of Pasteurellae and their antibiogram susceptibility pattern in Haramaya District, Eastern Hararghe, Ethiopia.

Publisher: BioMed Central Country of Publication: England NLM ID: 101249759 Publication Model: Electronic Cited Medium: Internet ISSN: 1746-6148 (Electronic) Linking ISSN: 17466148 NLM ISO Abbreviation: BMC Vet Res Subsets: MEDLINE

Original Publication: London : BioMed Central, 2005-

Anti-Bacterial Agents/*therapeutic use ; Pasteurella/*drug effects ; Pasteurella Infections/*veterinary ; Sheep Diseases/*microbiology; Animals ; Cross-Sectional Studies ; Ethiopia/epidemiology ; Female ; Lung/microbiology ; Male ; Mannheimia haemolytica/drug effects ; Mannheimia haemolytica/isolation & purification ; Microbial Sensitivity Tests/veterinary ; Nasal Cavity/microbiology ; Pasteurella/isolation & purification ; Pasteurella Infections/drug therapy ; Pasteurella Infections/epidemiology ; Pasteurella Infections/microbiology ; Pasteurella multocida/drug effects ; Pasteurella multocida/isolation & purification ; Pneumonia, Bacterial/drug therapy ; Pneumonia, Bacterial/microbiology ; Pneumonia, Bacterial/veterinary ; Sheep ; Sheep Diseases/drug therapy

Background: Sheep constitute the second major component of livestock in Ethiopia. However, efficient utilization of this potential resource is hampered by combination of health problems, poor management and feed shortage. Haramaya district is one of the remote settings in Ethiopia where information about the livestock disease is not well documented. Hence this study was conducted to determine the causative agents and their antimicrobial susceptibility pattern of bacterial Pasteurella isolates among pneumonic ovine in Haramaya district, Eastern Hararghe, Ethiopia.
Results: Out of 256 samples examined, Pasteurella was isolated in 64 (25%), of which 38 (59.4%) were from lungs and 26 (40.6%) were from nasal cavities. 87.5% of the isolates were Mannheimia haemolytica and 12.5% were Pasteurella multocida. All of the isolates from the lungs were Mannheimia haemolytica whereas 69% of the isolates from nasals cavities were Mannheimia haemolytica. Age and body temperature were significantly associated with Pasteurella isolates from clinic (P < 0.05). Despite diverse in the site of origins, the isolates exhibited uniformity in sensitivity to a majority of the antibacterial agents. The most effective drug was Cholramphenicol (100%) followed by Sulfamethoxazole (89.1%) and Tetracycline (84.4%). Both species were completely resistant to Gentamycin and Vancomycin.
Conclusion: Mannheimia haemolytica is the most common cause of ovine pneumonic pasteurellosis in the study area. The isolates were susceptible to limited antimicrobial agents. Therefore, the antimicrobial susceptibility test should be conducted before treatment, except for critical cases.

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0 (Anti-Bacterial Agents)

Date Created: 20131203 Date Completed: 20140813 Latest Revision: 20220408

20240829

PMC4220828

10.1186/1746-6148-9-239

24289236