Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request

The challenge of causal inference in gene-environment interaction research: leveraging research designs from the social sciences.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي
  • المؤلفون: Fletcher JM;Fletcher JM; Conley D
  • المصدر:
    American journal of public health [Am J Public Health] 2013 Oct; Vol. 103 Suppl 1, pp. S42-5. Date of Electronic Publication: 2013 Aug 08.
  • نوع النشر :
    Journal Article; Research Support, Non-U.S. Gov't
  • اللغة:
    English
  • معلومة اضافية
    • المصدر:
      Publisher: American Public Health Association Country of Publication: United States NLM ID: 1254074 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1541-0048 (Electronic) Linking ISSN: 00900036 NLM ISO Abbreviation: Am J Public Health Subsets: MEDLINE
    • بيانات النشر:
      Publication: Washington, DC : American Public Health Association
      Original Publication: New York [etc.]
    • الموضوع:
      Causality* ; Gene-Environment Interaction* ; Genetic Research* ; Social Sciences*; Humans ; Research Design
    • نبذة مختصرة :
      The integration of genetics and the social sciences will lead to a more complex understanding of the articulation between social and biological processes, although the empirical difficulties inherent in this integration are large. One key challenge is the implications of moving "outside the lab" and away from the experimental tools available for research with model organisms. Social science research methods used to examine human behavior in nonexperimental, real-world settings to date have not been fully taken advantage of during this disciplinary integration, especially in the form of gene-environment interaction research. This article outlines and provides examples of several prominent research designs that should be used in gene-environment research and highlights a key benefit to geneticists of working with social scientists.
    • References:
      J Health Econ. 2011 Jul;30(4):647-59. (PMID: 21664708)
      JAMA. 2009 Jun 17;301(23):2462-71. (PMID: 19531786)
      Arch Gen Psychiatry. 2011 May;68(5):444-54. (PMID: 21199959)
      J Econ Perspect. 2011 Spring;25(2):133-56. (PMID: 21595328)
      Biodemography Soc Biol. 2009;55(2):238-51. (PMID: 20183907)
      PLoS One. 2010 Feb 22;5(2):e9352. (PMID: 20179766)
      J Health Soc Behav. 2013 Mar;54(1):109-27. (PMID: 23475742)
      Health Econ. 2011 Aug;20(8):889-92. (PMID: 21612001)
      Biometrics. 1999 Dec;55(4):997-1004. (PMID: 11315092)
      Nat Genet. 2006 Aug;38(8):904-9. (PMID: 16862161)
      Int J Epidemiol. 2009 Feb;38(1):3-6. (PMID: 19052115)
      Arch Pediatr Adolesc Med. 2003 Jun;157(6):572-8. (PMID: 12796238)
      Biol Psychiatry. 2009 Feb 1;65(3):211-9. (PMID: 18691701)
      Nat Rev Genet. 2010 Jun;11(6):446-50. (PMID: 20479774)
      Science. 2003 Jul 18;301(5631):386-9. (PMID: 12869766)
      PLoS One. 2012;7(12):e50576. (PMID: 23227187)
      Nat Rev Genet. 2010 Jul;11(7):459-63. (PMID: 20548291)
    • الموضوع:
      Date Created: 20130810 Date Completed: 20131112 Latest Revision: 20240323
    • الموضوع:
      20240323
    • الرقم المعرف:
      PMC3786757
    • الرقم المعرف:
      10.2105/AJPH.2013.301290
    • الرقم المعرف:
      23927518