Item request has been placed!
×
Item request cannot be made.
×
Processing Request
NXCL-4950, a novel composite applicable to peripheral skin, is capable of increasing skin temperature by enhancing capillary circulation.
Item request has been placed!
×
Item request cannot be made.
×
Processing Request
- المؤلفون: Kim DC;Kim DC; Lee CE
- المصدر:
Clinical and experimental dermatology [Clin Exp Dermatol] 2013 Apr; Vol. 38 (3), pp. 244-50. Date of Electronic Publication: 2012 Sep 25.
- نوع النشر :
Journal Article; Research Support, Non-U.S. Gov't
- اللغة:
English
- معلومة اضافية
- المصدر:
Publisher: Oxford University Press Country of Publication: England NLM ID: 7606847 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2230 (Electronic) Linking ISSN: 03076938 NLM ISO Abbreviation: Clin Exp Dermatol Subsets: MEDLINE
- بيانات النشر:
Publication: 2023- : Oxford : Oxford University Press
Original Publication: Oxford : Blackwell Scientific Publications.
- الموضوع:
- نبذة مختصرة :
Background: Rapid skin warming and prompt correct medical treatment lead to dramatic improvement in patients with peripheral capillary-related damage, such as injuries, Raynaud disease and frostbite.
Aim: To characterize a novel composite, NXCL-4950, for use in a cosmetic lotion.
Methods: The effects of NXCL-4950 on enhancing skin blood flow, skin temperature warming, and expansion of peripheral blood vessels and scalp microvessels were investigated.
Results: Monitoring by laser Doppler perfusion imaging and thermal imaging showed that application of NXCL-4950 to the hands increased skin blood flow and temperature relative to the control (or placebo) group. For the 20 participants with a high Raynaud Condition Score, application of NXCL-4950 to the skin resulted in a mean increase of 215.53% in microvessel diameter and mean increase of 164.96% in the speed of blood flow. When NXCL-4950 was applied to the scalp, the microvessels around the hair roots were clearly visible after 20 min.
Conclusion: NXCL-4950 is a potential candidate for enhancing peripheral skin temperature, and might be useful in the treatment of capillary-related disorders.
(© The Author(s). CED © 2012 British Association of Dermatologists.)
- الرقم المعرف:
0 (Complex Mixtures)
0 (NXCL-4950)
0 (Plant Extracts)
0 (Vasodilator Agents)
- الموضوع:
Date Created: 20120926 Date Completed: 20130917 Latest Revision: 20130322
- الموضوع:
20221213
- الرقم المعرف:
10.1111/j.1365-2230.2012.04371.x
- الرقم المعرف:
23006135
No Comments.