Steam-cooking rapidly destroys and reverses onion-induced antiplatelet activity.

Publisher: BioMed Central Country of Publication: England NLM ID: 101152213 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2891 (Electronic) Linking ISSN: 14752891 NLM ISO Abbreviation: Nutr J Subsets: MEDLINE

Original Publication: London : BioMed Central, 2002-

Cooking*; Onions/*chemistry ; Plant Extracts/*pharmacology ; Plant Roots/*chemistry ; Plants, Medicinal/*chemistry ; Platelet Aggregation/*drug effects ; Platelet Aggregation Inhibitors/*pharmacology; Adult ; Aged ; Chimera ; Female ; Humans ; Male ; Middle Aged ; Plant Extracts/chemistry ; Platelet Aggregation Inhibitors/chemistry ; Polyphenols/analysis ; Steam/adverse effects ; Time Factors ; Young Adult

Background: Foods in the diet that can aid in the prevention of diseases are of major interest. Onions are key ingredients in many cuisines around the world and moreover, onion demand has trended higher over the past three decades. An important pharmacological aspect of onion is the ability to inhibit platelet aggregation. Raw onions inhibit platelet aggregation; however, when onions are boiled or heated, antiplatelet activity may be abolished.
Methods: Onion quarters were steamed for 0, 1, 3, 6, 10, and 15 min. The in vitro antiplatelet activity of a yellow hybrid storage onion was examined at these times on the blood of 12 human subjects using in vitro whole blood aggregometry.
Results: Contrary to findings reported for boiling, antiplatelet activity was destroyed between 3 and 6 min of steaming, and at 10 min of steaming, cooked onions stimulated platelet activity. Extracts from cooked onion had the potential to reverse the inhibitory effect on blood platelets by 25%. Responses were consistent across all donors. Total polyphenolic concentration and soluble solids were not affected by steaming time.
Conclusions: The potential value of cooked onion preparations may result in destruction or reversal of antiplatelet activity, without affecting the polyphenolic concentration.

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0 (Plant Extracts)
0 (Platelet Aggregation Inhibitors)
0 (Polyphenols)
0 (Steam)

Date Created: 20120921 Date Completed: 20130412 Latest Revision: 20231106

20231215

PMC3490999

10.1186/1475-2891-11-76

22992282