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Examining fatigue in COPD: development, validity and reliability of a modified version of FACIT-F scale.

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  • معلومة اضافية
    • Corporate Authors:
    • المصدر:
      Publisher: BioMed Central Country of Publication: England NLM ID: 101153626 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-7525 (Electronic) Linking ISSN: 14777525 NLM ISO Abbreviation: Health Qual Life Outcomes Subsets: MEDLINE
    • بيانات النشر:
      Original Publication: [London] : BioMed Central, c2003-
    • الموضوع:
    • نبذة مختصرة :
      Introduction: Fatigue is a disruptive symptom that inhibits normal functional performance of COPD patients in daily activities. The availability of a short, simple, reliable and valid scale would improve assessment of the characteristics and influence of fatigue in COPD.
      Methods: At baseline, 2107 COPD patients from the ECLIPSE cohort completed the Functional Assessment of Chronic Illness Therapy Fatigue (FACIT-F) scale. We used well-structured classic method, the principal components analysis (PCA) and Rasch analysis for structurally examining the 13-item FACIT-F.
      Results: Four items were less able to capture fatigue characteristics in COPD and were deleted. PCA was applied to the remaining 9 items of the modified FACIT-F and resulted in three interpretable dimensions: i) general (5 items); ii) functional ability (2 items); and iii) psychosocial fatigue (2 items). The modified FACIT-F had high internal consistency (Cronbach's α = 0.91) and it did not fit a uni-dimensional Rasch model, confirming the prior output from the PCA. The correlations between total score and each dimension were ≥ 0.64 and within dimensions ≥0.43 (p < 0.001 for all).The original and modified FACIT-F had significant convergent validity; its scores were associated with SGRQ total score (0.69 and 0.7) and mMRC dyspnoea scores (0.48 and 0.47), (p = <0.001 for all). The scale had meaningful discriminating ability in identifying patients with poor exercise performance and more depressive symptoms.
      Conclusion: The original and modified FACIT-F are valid and reliable scales in COPD. The modified version is shorter and measures not only total fatigue but also its sub-components in COPD.
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    • Molecular Sequence:
      ClinicalTrials.gov NCT00292552
    • الرقم المعرف:
      0 (Bronchodilator Agents)
    • الموضوع:
      Date Created: 20120824 Date Completed: 20130409 Latest Revision: 20220409
    • الموضوع:
      20250114
    • الرقم المعرف:
      PMC3491053
    • الرقم المعرف:
      10.1186/1477-7525-10-100
    • الرقم المعرف:
      22913289