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Associations between oxidative parameters in pregnancy and birth anthropometry in a cohort of women and children in rural Bangladesh: the MINIMat-cohort.

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اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي
  • المؤلفون: Lindström E;Lindström E; Persson LÅ; Raqib R; El Arifeen S; Basu S; Ekström EC
  • المصدر:
    Free radical research [Free Radic Res] 2012 Mar; Vol. 46 (3), pp. 253-64. Date of Electronic Publication: 2012 Feb 06.
  • نوع النشر :
    Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • اللغة:
    English
  • معلومة اضافية
    • المصدر:
      Publisher: Informa Healthcare Country of Publication: England NLM ID: 9423872 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1029-2470 (Electronic) Linking ISSN: 10292470 NLM ISO Abbreviation: Free Radic Res Subsets: MEDLINE
    • بيانات النشر:
      Publication: London : Informa Healthcare
      Original Publication: Yverdon, Switzerland : New York, NY : Harwood Academic ; distributed by STBS Ltd., c1994-
    • الموضوع:
      Anthropometry* ; Oxidative Stress*; Deoxyguanosine/*analogs & derivatives ; Dinoprost/*analogs & derivatives ; Pregnancy/*metabolism; 8-Hydroxy-2'-Deoxyguanosine ; Adult ; Bangladesh/epidemiology ; Biomarkers ; Birth Weight ; Cohort Studies ; DNA Damage ; Deoxyguanosine/urine ; Dietary Supplements ; Dinoprost/urine ; Female ; Gestational Age ; Humans ; Infant, Newborn ; Lipid Peroxidation ; Male ; Sampling Studies ; Young Adult
    • نبذة مختصرة :
      Oxidative stress is suggested as a potential mechanism in impaired foetal growth, smaller birth size and thus subsequently adult chronic diseases. We have investigated associations between oxidative stress in pregnancy and birth anthropometry (weight, height, head and chest circumferences). In the MINIMat-trial (Maternal and Infant Nutrition Interventions, Matlab) in rural Bangladesh, free 8-iso-prostaglandin F(2α) (lipid peroxidation) was analysed in pregnancy week 14 and 30 and 8-Hydroxy-2 -Deoxyguanosine (DNA oxidation) in week 19. We found that higher levels of lipid peroxidation in early pregnancy were associated with larger infant size (birth length and chest circumference). In late pregnancy, no clear pattern of associations was found. Increasing level of DNA oxidation was associated with lower birth length in girls but no other associations were found. In conclusion, a higher level of lipid peroxidation in early (but not late) pregnancy was associated with a favourable larger birth size suggesting that timing of lipid peroxidation is of importance.
    • الرقم المعرف:
      0 (Biomarkers)
      27415-26-5 (8-epi-prostaglandin F2alpha)
      88847-89-6 (8-Hydroxy-2'-Deoxyguanosine)
      B7IN85G1HY (Dinoprost)
      G9481N71RO (Deoxyguanosine)
    • الموضوع:
      Date Created: 20120113 Date Completed: 20120626 Latest Revision: 20191210
    • الموضوع:
      20221213
    • الرقم المعرف:
      10.3109/10715762.2011.651467
    • الرقم المعرف:
      22236270