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The effects of detraining on blood adipokines and antioxidant enzyme in Korean overweight children.

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  • المؤلفون: Woo J;Woo J; Shin KO; Yoo JH; Park S; Kang S
  • المصدر:
    European journal of pediatrics [Eur J Pediatr] 2012 Feb; Vol. 171 (2), pp. 235-43. Date of Electronic Publication: 2011 Jun 24.
  • نوع النشر :
    Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • اللغة:
    English
  • معلومة اضافية
    • المصدر:
      Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7603873 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1076 (Electronic) Linking ISSN: 03406199 NLM ISO Abbreviation: Eur J Pediatr Subsets: MEDLINE
    • بيانات النشر:
      Publication: Berlin : Springer Verlag
      Original Publication: Berlin, New York, Springer-Verlag.
    • الموضوع:
      Adiponectin/*blood ; Exercise/*physiology ; Glutathione Peroxidase/*blood ; Leptin/*blood ; Overweight/*physiopathology ; Superoxide Dismutase/*blood; Antioxidants/metabolism ; Biomarkers/blood ; Body Composition ; Child ; Cholesterol/blood ; Exercise Test ; Humans ; Leukocytes, Mononuclear/metabolism ; Male ; Obesity/blood ; Obesity/physiopathology ; Overweight/blood ; Republic of Korea ; Reverse Transcriptase Polymerase Chain Reaction ; Triglycerides/blood
    • نبذة مختصرة :
      The present study examined the change to clarify the effects of detraining on the concentration of lipid profiles, serum adipokines and antioxidant enzyme gene expression in Korean overweight children. The subjects were normal children (n = 19) and obese children (n = 20) who were further subdivided into the overweight training (OT) group (n = 10) and the overweight detraining (OD) group (n = 10). Maximal oxygen uptake (VO(2)max); body composition; lipid profiles (TG, TC); adipokines (adiponectin and leptin); antioxidants (blood and gene expressions SOD and GPX) were measured before, 12 weeks, and 24 weeks after the exercise program. Body mass index (BMI) and %fat were significantly higher in the OD group only. However, waist hip ration (WHR) and systolic blood pressure (SBP) were significantly decreased in the OT group. TG was significantly decreased in the OT group. There was a significant difference in TG level between the two groups. Besides, adiponectin was significantly increased in both the OT group and the OD group. Furthermore, leptin was significantly decreased in the OT group. There was a significant difference in leptin level between the two groups. In training groups, the expression of SOD was significantly increased after a 12- and 24-week period (p < 0.05). However, detraining group was significantly increased after a 12-week only (p < 0.05). In addition, GPX was significantly increased after a 24-week only in the training group (p < 0.05). Thus, detraining showed that negative effected on body composition and lipid profiles and maintained of uniform period on adipokines and antioxidant enzyme the protein and expression.
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    • الرقم المعرف:
      0 (Adiponectin)
      0 (Antioxidants)
      0 (Biomarkers)
      0 (Leptin)
      0 (Triglycerides)
      97C5T2UQ7J (Cholesterol)
      EC 1.11.1.9 (Glutathione Peroxidase)
      EC 1.15.1.1 (Superoxide Dismutase)
    • الموضوع:
      Date Created: 20110625 Date Completed: 20120911 Latest Revision: 20211020
    • الموضوع:
      20240829
    • الرقم المعرف:
      10.1007/s00431-011-1518-2
    • الرقم المعرف:
      21701811