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[Yeast as a model for studying neurodegeneration].

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  • المؤلفون: Wawrzycka D;Wawrzycka D
  • المصدر:
    Postepy higieny i medycyny doswiadczalnej (Online) [Postepy Hig Med Dosw (Online)] 2011 Jun 02; Vol. 65, pp. 328-37. Date of Electronic Publication: 2011 Jun 02.
  • نوع النشر :
    Journal Article; Review
  • اللغة:
    Polish
  • معلومة اضافية
    • Transliterated Title:
      Drożdże jako model w badaniach chorób neurodegeneracyjnych.
    • المصدر:
      Publisher: Medical Science International Country of Publication: Poland NLM ID: 101206517 Publication Model: Electronic Cited Medium: Internet ISSN: 1732-2693 (Electronic) Linking ISSN: 00325449 NLM ISO Abbreviation: Postepy Hig Med Dosw (Online) Subsets: MEDLINE
    • بيانات النشر:
      Original Publication: [Warsaw, Poland] : Medical Science International, [2004]-
    • الموضوع:
      Models, Neurological*; Neurodegenerative Diseases/*physiopathology ; Saccharomyces cerevisiae/*genetics ; Saccharomyces cerevisiae/*physiology; Humans
    • نبذة مختصرة :
      At the level of genetics and physiology the yeast Saccharomyces cerevisiae is are the best characterized eukaryotic cells. The yeast cells can be used as a model to study the mechanisms involved in human disease. Yeast shares conserved cellular mechanisms with all eukaryotes including mammals and human. Nowadays, despite the lack of a neural system, yeasts are successfully used in the study of neurodegenerative disorders such as Alzheimer’s disease, Huntington’s disease and Parkinson’s disease. Exquisite genetics and molecular tools used in biology allow examination of the role of yeast homologues of human genes as well as heterologous expression of human genes in yeast. Yeasts have become a suitable model to study the causes of pathological changes in protein folding, mutations and formation of aggregates.
    • الموضوع:
      Date Created: 20110617 Date Completed: 20120105 Latest Revision: 20201209
    • الموضوع:
      20231215
    • الرقم المعرف:
      10.5604/17322693.945767
    • الرقم المعرف:
      21677357