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Whooping cough in Pakistan: Bordetella pertussis vs Bordetella parapertussis in 2005-2009.

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اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي
  • المؤلفون: Bokhari H;Bokhari H; Said F; Syed MA; Mughal A; Kazi YF; Heuvelman K; Mooi FR
  • المصدر:
    Scandinavian journal of infectious diseases [Scand J Infect Dis] 2011 Oct; Vol. 43 (10), pp. 818-20. Date of Electronic Publication: 2011 May 12.
  • نوع النشر :
    Journal Article; Research Support, Non-U.S. Gov't
  • اللغة:
    English
  • معلومة اضافية
    • المصدر:
      Publisher: Informa Healthcare Country of Publication: England NLM ID: 0215333 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1651-1980 (Electronic) Linking ISSN: 00365548 NLM ISO Abbreviation: Scand J Infect Dis Subsets: MEDLINE
    • بيانات النشر:
      Publication: 2007-2014 : London : Informa Healthcare
      Original Publication: Stockholm, Society for the Publication of Acta medica Scandinavica.
    • الموضوع:
      Bordetella parapertussis/*isolation & purification ; Bordetella pertussis/*isolation & purification ; Whooping Cough/*microbiology; Bordetella parapertussis/genetics ; Bordetella pertussis/genetics ; Cohort Studies ; Electrophoresis, Agar Gel ; Humans ; Pakistan/epidemiology ; Polymerase Chain Reaction ; Whooping Cough/epidemiology
    • نبذة مختصرة :
      Pertussis, or whooping cough, is an acute respiratory disease mainly affecting infants and children and is caused by Bordetella pertussis and Bordetella parapertussis. The aim of this study was to investigate the share of Bordetella species from potential whooping cough cases during 2005-2009. Eight hundred and two samples from suspected pertussis cases were collected, mainly from 2 provinces of Pakistan. Bacterial culture, identification, DNA extraction and routinely used polymerase chain reaction (PCR) methods using IS1001, IS1002 and IS481 were used to identify the Bordetella species. The results were unexpected, because all of the isolates collected from the different cities were identified as B. parapertussis (7.4%); B. pertussis was not isolated from any sample. However, PCR results indicated the presence of a small percentage (0.6%) of B. pertussis among the total cases studied. This study suggests that vaccines to protect against both B. pertussis and B. parapertussis should be considered.
    • الموضوع:
      Date Created: 20110514 Date Completed: 20120302 Latest Revision: 20110905
    • الموضوع:
      20240829
    • الرقم المعرف:
      10.3109/00365548.2011.577804
    • الرقم المعرف:
      21563881