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Virtual reality exposure therapy as treatment for pain catastrophizing in fibromyalgia patients: proof-of-concept study (Study Protocol).

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  • المؤلفون: Morris LD;Morris LD; Grimmer-Somers KA; Spottiswoode B; Louw QA
  • المصدر:
    BMC musculoskeletal disorders [BMC Musculoskelet Disord] 2011 Apr 30; Vol. 12 (1), pp. 85. Date of Electronic Publication: 2011 Apr 30.
  • نوع النشر :
    Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • اللغة:
    English
  • معلومة اضافية
    • المصدر:
      Publisher: BioMed Central Country of Publication: England NLM ID: 100968565 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2474 (Electronic) Linking ISSN: 14712474 NLM ISO Abbreviation: BMC Musculoskelet Disord Subsets: MEDLINE
    • بيانات النشر:
      Original Publication: London : BioMed Central, [2000-
    • الموضوع:
      Implosive Therapy* ; Pain Management* ; Research Design* ; User-Computer Interface*; Brain/*physiopathology ; Catastrophization/*therapy ; Exercise Therapy/*psychology ; Fibromyalgia/*therapy; Catastrophization/etiology ; Catastrophization/physiopathology ; Catastrophization/psychology ; Fibromyalgia/complications ; Fibromyalgia/physiopathology ; Fibromyalgia/psychology ; Humans ; Magnetic Resonance Imaging ; Neuropsychological Tests ; Pain/etiology ; Pain/physiopathology ; Pain/psychology ; Pain Measurement ; Patient Compliance ; Photic Stimulation ; South Africa ; Treatment Outcome
    • نبذة مختصرة :
      Background: Albeit exercise is currently advocated as one of the most effective management strategies for fibromyalgia syndrome (FMS); the implementation of exercise as a FMS treatment in reality is significantly hampered by patients' poor compliance. The inference that pain catastrophizing is a key predictor of poor compliance in FMS patients, justifies considering the alteration of pain catastrophizing in improving compliance towards exercises in FMS patients. The aim of this study is to provide proof-of-concept for the development and testing of a novel virtual reality exposure therapy (VRET) program as treatment for exercise-related pain catastrophizing in FMS patients.
      Methods: Two interlinked experimental studies will be conducted. Study 1 aims to objectively ascertain if neurophysiological changes occur in the functional brain areas associated with pain catastrophizing, when catastrophizing FMS subjects are exposed to visuals of exercise activities. Study 2 aims to ascertain the preliminary efficacy and feasibility of exposure to visuals of exercise activities as a treatment for exercise-related pain catastrophizing in FMS subjects. Twenty subjects will be selected from a group of FMS patients attending the Tygerberg Hospital in Cape Town, South Africa and randomly allocated to either the VRET (intervention) group or waiting list (control) group. Baseline neurophysiological activity for subjects will be collected in study 1 using functional magnetic resonance imaging (fMRI). In study 2, clinical improvement in pain catastrophizing will be measured using fMRI (objective) and the pain catastrophizing scale (subjective).
      Discussion: The premise is if exposing FMS patients to visuals of various exercise activities trigger the functional brain areas associated with pain catastrophizing; then as a treatment, repeated exposure to visuals of the exercise activities using a VRET program could possibly decrease exercise-related pain catastrophizing in FMS patients. Proof-of-concept will either be established or negated. The results of this project are envisaged to revolutionize FMS and pain catastrophizing research and in the future, assist health professionals and FMS patients in reducing despondency regarding FMS management.
      Trial Registration: PACTR201011000264179.
    • References:
      Arthritis Rheum. 2000 Nov;43(11):2493-500. (PMID: 11083273)
      Arthritis Rheum. 2006 Apr 15;55(2):325-32. (PMID: 16583384)
      Trials. 2009 Apr 23;10:24. (PMID: 19389246)
      BMC Public Health. 2010 Apr 20;10:198. (PMID: 20406476)
      Nat Rev Rheumatol. 2009 Apr;5(4):191-9. (PMID: 19337283)
      Ann Rheum Dis. 2007 May;66(5):571-81. (PMID: 16916856)
      Prev Med. 2002 Oct;35(4):383-9. (PMID: 12453716)
      Neuroimage. 2004;23 Suppl 1:S208-19. (PMID: 15501092)
      Eur J Pain. 2004 Oct;8(5):495-502. (PMID: 15324781)
      Semin Arthritis Rheum. 2008 Jun;37(6):353-65. (PMID: 17976693)
      Brain. 2004 Apr;127(Pt 4):835-43. (PMID: 14960499)
      J Rheumatol. 1991 May;18(5):728-33. (PMID: 1865419)
      Arthritis Res Ther. 2009;11(4):R120. (PMID: 19664287)
      Clin J Pain. 2010 May;26(4):284-90. (PMID: 20393262)
      J Pain. 2009 Aug;10(8):777-91. (PMID: 19638325)
      Pharmacoeconomics. 2009;27(7):547-59. (PMID: 19663526)
      J Clin Psychiatry. 2008;69 Suppl 2:4-5. (PMID: 18537456)
      Curr Opin Rheumatol. 2004 Mar;16(2):157-63. (PMID: 14770104)
      Actas Esp Psiquiatr. 2008 Jul-Aug;36(4):223-6. (PMID: 18461496)
      Arthritis Res Ther. 2010;12(3):R79. (PMID: 20459730)
      BMJ. 2002 Jul 27;325(7357):185. (PMID: 12142304)
      J Anxiety Disord. 2008;22(3):561-9. (PMID: 17544252)
      Rheum Dis Clin North Am. 2009 May;35(2):373-91. (PMID: 19647149)
      J Behav Ther Exp Psychiatry. 2008 Sep;39(3):250-61. (PMID: 17720136)
      Orthop Nurs. 2006 May-Jun;25(3):205-14. (PMID: 16735853)
    • الموضوع:
      Date Created: 20110503 Date Completed: 20111007 Latest Revision: 20211020
    • الموضوع:
      20250114
    • الرقم المعرف:
      PMC3114800
    • الرقم المعرف:
      10.1186/1471-2474-12-85
    • الرقم المعرف:
      21529375