Relationship of the Brief UCSD Performance-based Skills Assessment (UPSA-B) to multiple indicators of functioning in people with schizophrenia and bipolar disorder.

Publisher: Wiley-Blackwell Munksgaard Country of Publication: Denmark NLM ID: 100883596 Publication Model: Print Cited Medium: Internet ISSN: 1399-5618 (Electronic) Linking ISSN: 13985647 NLM ISO Abbreviation: Bipolar Disord Subsets: MEDLINE

Publication: Copenhagen : Wiley-Blackwell Munksgaard
Original Publication: Copenhagen, Denmark : Munksgaard, 1999-

Activities of Daily Living* ; Neuropsychological Tests* ; Psychiatric Status Rating Scales* ; Schizophrenic Psychology*; Bipolar Disorder/*physiopathology ; Bipolar Disorder/*psychology ; Schizophrenia/*physiopathology; Adult ; Bipolar Disorder/diagnosis ; Cognition Disorders/diagnosis ; Cognition Disorders/etiology ; Disability Evaluation ; Employment ; Female ; Follow-Up Studies ; Humans ; Independent Living ; Male ; Middle Aged ; Quality of Life ; Schizophrenia/diagnosis ; Severity of Illness Index ; Social Behavior ; Statistics as Topic ; Substance-Related Disorders/diagnosis

Objective: This study assessed the relationship between multiple indicators of 'real-world' functioning and scores on a brief performance-based measure of functional capacity known as the Brief University of California San Diego (UCSD) Performance-based Skills Assessment (UPSA-B) in a sample of 205 patients with either serious bipolar disorder (n = 89) or schizophrenia (n = 116).
Methods: Participants were administered the UPSA-B and assessed on the following functional domains: (i) independent living status (e.g., residing independently as head of household, living in residential care facility); (ii) informant reports of functioning (e.g., work skills, daily living skills); (iii) educational attainment and estimated premorbid IQ as measured by years of education and Wide Range Achievement Test reading scores, respectively; and (iv) employment.
Results: Better scores on the UPSA-B were associated with greater residential independence after controlling for age, diagnosis, and symptoms of psychopathology. Among both bipolar disorder and schizophrenia patients, higher UPSA-B scores were significantly related to better informant reports of functioning in daily living skills and work skills domains. Greater estimated premorbid IQ was associated with higher scores on the UPSA-B for both schizophrenia and bipolar disorder participants. Participants who were employed scored higher on the UPSA-B when controlling for age and diagnosis, but not when controlling for symptoms of psychopathology.
Conclusions: These data suggest the UPSA-B may be useful for assessing capacity for functioning in a number of domains in both people diagnosed with schizophrenia and bipolar disorder.

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R01MH079784 United States MH NIMH NIH HHS; R01 MH084967-01A1 United States MH NIMH NIH HHS; R01 MH078737 United States MH NIMH NIH HHS; K23 MH077225 United States MH NIMH NIH HHS; R01 MH079784 United States MH NIMH NIH HHS; R01 MH078775 United States MH NIMH NIH HHS; R01 MH084967 United States MH NIMH NIH HHS; R01MH078737 United States MH NIMH NIH HHS; R01MH078775 United States MH NIMH NIH HHS; K23MH077225 United States MH NIMH NIH HHS

Date Created: 20100213 Date Completed: 20100429 Latest Revision: 20220331

20240829

PMC2846793

10.1111/j.1399-5618.2009.00787.x

20148866