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Efficient Delivery of siRNA Targeted Against Human Papillomavirus Oncogenes.

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  • معلومة اضافية
    • الموضوع:
      BIOLOGICAL reagents; SMALL interfering RNA; PAPILLOMAVIRUSES; MESSENGER RNA; CELLS
    • نبذة مختصرة :
      The article evaluates the efficiency of transfection reagents in the delivery of small interfering RNA targeted against human papillomavirus (HPV). The X-tremeGENE small interfering Transfection Reagent has a transfection efficiency of 80 to 90 percent. A reduction of HPV18 E6⁄E7 messenger RNA levels in the lanes containing the HPV18 E6⁄E7 small interfering RNA transfected cells with transfection reagents over the respective mock-transfected cells was observed.